评估使用 Finesse™ Flex Loop 进行自体视网膜自体移植治疗失败性黄斑裂孔的功能和解剖学结果。

To evaluate the functional and anatomical outcomes for autologous retinal autograft with Finesse™ Flex Loop for failed macular holes.

机构信息

Vitreo Retina, Dhami Eye Care Hospital, Ludhiana, Punjab, India.

Medical Retina Services, Dhami Eye Care Hospital, Ludhiana, Punjab, India.

出版信息

Indian J Ophthalmol. 2022 Aug;70(8):3033-3037. doi: 10.4103/ijo.IJO_3215_21.

DOI:10.4103/ijo.IJO_3215_21

PMID:35918967

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9672773/

Abstract

PURPOSE

To evaluate the functional and anatomical outcomes for autologous retinal autograft with Finesse™ Flex Loop for failed macular holes.

METHODS

This is a retrospective study analyzing medical records of consecutive patients with refractory macular hole (at least 1 prior surgery) and eyes with retinal detachment with coexisting macular holes (MH). Optical coherence tomography (OCT) of the macula was performed before and after surgery. The primary study outcome evaluated were the functional and anatomic macular hole closure, and secondary outcomes were improvement in visual acuity and restoration of the outer retinal bands, external limiting membrane, and ellipsoid zone in eyes with acquisition of autologous retinal transplant using Finesse Loop.

RESULTS

The study included eight eyes of eight patients; retinal autograft was performed in six (75.0%) and autologous retinal transplantation (ART) with rhegmatogenous retinal detachment (RRD) was performed in two (25.0%) eyes. The average MH basal diameter in the study was 1310.88 ± 138.63 μm. The successful hole closure rate was observed to be 75% (6 eyes) and 100% retinal reattachment was observed in ART with RRD. Statistically significant (P = 0.001) improvement was noted for preop and postop visual acuity gain for ART acquisition and postop macular hole closure. The restoration of the external limiting membrane (ELM) and ellipsoid zone (EZ) was observed in 37.5% (3 eyes) of patients.

CONCLUSION

Finesse™ Flex Loop can be used to harvest retinal tissue and it provides good anatomical and functional outcomes for failed macular hole.

摘要

目的

评估使用 Finesse™ Flex Loop 进行自体视网膜移植治疗失败性黄斑裂孔的功能和解剖结果。

方法

这是一项回顾性研究，分析了连续患有难治性黄斑裂孔（至少有 1 次先前手术）和伴有黄斑裂孔的视网膜脱离（MH）的患者的病历。手术前后均进行黄斑光学相干断层扫描（OCT）。主要研究结果评估为黄斑裂孔的功能和解剖闭合，次要结果为视力改善和使用 Finesse Loop 获取自体视网膜移植后外视网膜带、外部限制膜和椭圆体区的恢复。

结果

该研究包括 8 例 8 只眼；6 只眼（75.0%）行视网膜自体移植，2 只眼（25.0%）行伴孔源性视网膜脱离（RRD）的自体视网膜移植（ART）。研究中平均 MH 基底部直径为 1310.88±138.63μm。观察到成功闭合率为 75%（6 只眼），RRD 行 ART 观察到 100%的视网膜再附着。ART 获得和术后黄斑裂孔闭合的术前和术后视力提高均有统计学意义（P=0.001）。在 37.5%（3 只眼）的患者中观察到外部限制膜（ELM）和椭圆体区（EZ）的恢复。