德国无菌性骨不连的流行病学及直接医疗费用——一项描述性报告
The epidemiology and direct healthcare costs of aseptic nonunions in Germany - a descriptive report.
作者信息
Walter Nike, Hierl Katja, Brochhausen Christoph, Alt Volker, Rupp Markus
机构信息
Department for Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.
Department for Psychosomatic Medicine, University Medical Center Regensburg, Regensburg, Germany.
出版信息
Bone Joint Res. 2022 Aug;11(8):541-547. doi: 10.1302/2046-3758.118.BJR-2021-0238.R3.
AIMS
This observational cross-sectional study aimed to answer the following questions: 1) how has nonunion incidence developed from 2009 to 2019 in a nationwide cohort; 2) what is the age and sex distribution of nonunions for distinct anatomical nonunion localizations; and 3) how high were the costs for surgical nonunion treatment in a level 1 trauma centre in Germany?
METHODS
Data consisting of annual International Classification of Diseases (ICD)-10 diagnosis codes from German medical institutions from 2009 to 2019, provided by the Federal Statistical Office of Germany (Destatis), were analyzed. Nonunion incidence was calculated for anatomical localization, sex, and age groups. Incidence rate ratios (IRRs) were determined and compared with a two-sample z-test. Diagnosis-related group (DRG)-reimbursement and length of hospital stay were retrospectively retrieved for each anatomical localization, considering 210 patients.
RESULTS
In 2019, a total of 11,840 nonunion cases (17.4/100,000 inhabitants) were treated. In comparison to 2018, the incidence of nonunion increased by 3% (IRR 1.03, 95% confidence interval (CI) 0.53 to 1.99, p = 0.935). The incidence was higher for male cases (IRR female/male: 0.79, 95% CI 0.76 to 0.82, p = 0.484). Most nonunions occurred at the pelvic and hip region (3.6/100,000 inhabitants, 95% CI 3.5 to 3.8), followed by the ankle and foot as well as the hand (2.9/100,000 inhabitants each). Mean estimated DRG reimbursement for in-hospital treatment of nonunions was highest for nonunions at the pelvic and hip region (€8,319 (SD 2,410), p < 0.001).
CONCLUSION
Despite attempts to improve fracture treatment in recent years, nonunions remain a problem for orthopaedic and trauma surgery, with a stable incidence throughout the last decade.Cite this article: 2022;11(8):541-547.
目的
本观察性横断面研究旨在回答以下问题:1)在全国队列中,2009年至2019年骨不连发病率如何变化;2)不同解剖部位骨不连的年龄和性别分布情况;3)德国一家一级创伤中心手术治疗骨不连的费用有多高?
方法
分析了由德国联邦统计局(德国联邦统计局)提供的2009年至2019年德国医疗机构的年度国际疾病分类(ICD)-10诊断代码数据。计算了不同解剖部位、性别和年龄组的骨不连发病率。确定发病率比(IRR),并通过双样本z检验进行比较。回顾性检索了210例患者每个解剖部位的诊断相关组(DRG)报销费用和住院时间。
结果
2019年,共治疗了11840例骨不连病例(17.4/10万居民)。与2018年相比,骨不连发病率增加了3%(IRR 1.03,95%置信区间(CI)0.53至1.99,p = 0.935)。男性病例的发病率更高(女性/男性IRR:0.79,95%CI 0.76至0.82,p = 0.484)。大多数骨不连发生在骨盆和髋部区域(3.6/10万居民,95%CI 3.5至3.8),其次是踝部和足部以及手部(各为2.9/10万居民)。骨盆和髋部区域骨不连的住院治疗平均估计DRG报销费用最高(8319欧元(标准差2410),p < 0.001)。
结论
尽管近年来一直在努力改善骨折治疗,但骨不连仍然是骨科和创伤外科面临的一个问题,在过去十年中发病率保持稳定。引用本文:2022;11(8):541-547。