全喉切除术中的唾液分流管：系统评价与荟萃分析。
Salivary bypass tube in total laryngectomy: Systematic review and meta-analysis.
作者信息
Costantino Andrea, Pace Gian Marco, Festa Bianca Maria, Ferreli Fabio, Malvezzi Luca, Spriano Giuseppe, Mercante Giuseppe, De Virgilio Armando
机构信息
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele MI, Italy.
Otorhinolaryngology Unit, IRCCS Humanitas Research Hospital, Rozzano MI, Italy.
出版信息
Head Neck. 2022 Nov;44(11):2608-2620. doi: 10.1002/hed.27169. Epub 2022 Aug 3.
The aim of this study is to determine whether the preventive positioning of a salivary bypass tube (SBT) after total laryngectomy (TL) reduces the incidence of postoperative pharyngocutaneous fistula (PCF) and pharyngeal stenosis (PS). This study was conducted in conformity with the PRISMA statement. 1960 patients with a median age of 62.0 years were included. A SBT was placed in 980 (50%) patients (SBT group). The cumulative PCF incidence in the SBT group was 15.8% (95% CI: 9.3-23.6). The measured pooled OR comparing PCF incidence in patients with SBT compared to those without was 0.40 (95% CI: 0.24-0.65). The pooled PS incidence in the SBT group was 12.3% (95% CI: 5.4-21.6). The measured pooled OR comparing PS incidence in patients with SBT compared to those without was 0.43 (95% CI: 0.24-0.65). PCF and PS could be prevented by the intra-operative placement of a SBT.
本研究的目的是确定全喉切除术后预防性放置唾液旁路管（SBT）是否能降低术后咽皮瘘（PCF）和咽狭窄（PS）的发生率。本研究是按照PRISMA声明进行的。纳入了1960例患者，中位年龄为62.0岁。980例（50%）患者放置了SBT（SBT组）。SBT组的累积PCF发生率为15.8%（95%CI：9.3 - 23.6）。与未放置SBT的患者相比，测量得到的比较SBT患者PCF发生率的合并OR为0.40（95%CI：0.24 - 0.65）。SBT组的合并PS发生率为12.3%（95%CI：5.4 - 21.6）。与未放置SBT的患者相比，测量得到的比较SBT患者PS发生率的合并OR为0.43（95%CI：0.24 - 0.65）。术中放置SBT可预防PCF和PS。
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