Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium.
Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium.
Clin Transplant. 2022 Sep;36(9):e14783. doi: 10.1111/ctr.14783. Epub 2022 Aug 16.
Heart donation after circulatory death (DCD) can significantly expand the heart donor pool, helping to overcome the problem of organ shortage and the increase in waiting list mortality and morbidity. To improve the outcome of DCD heart transplantation, thoraco-abdominal normothermic regional perfusion (TA-NRP) can be performed by selectively restoring circulation followed by in vivo functional heart assessment. Here, we report on the use of periprocedural transoesophageal echocardiography (TOE) as a minimally invasive cardiac assessment tool during different stages of a DCD heart procurement procedure using TA-NRP. We conclude that TOE is a valuable method to assess the donor heart for transplantation eligibility before and after withdrawal of life-sustaining therapy and during subsequent TA-NRP.
心脏在循环死亡（DCD）后捐献可以显著扩大心脏供体库，有助于解决器官短缺问题，降低等待名单上的死亡率和发病率。为了改善 DCD 心脏移植的结果，可以通过选择性恢复循环来进行胸腹部常温区域灌注（TA-NRP），然后进行体内功能性心脏评估。在这里，我们报告了在使用 TA-NRP 进行 DCD 心脏采集过程的不同阶段中，将经食管超声心动图（TOE）用作微创心脏评估工具的情况。我们得出结论，TOE 是一种在停止生命支持治疗前后以及随后进行 TA-NRP 期间评估供体心脏是否适合移植的有价值的方法。
