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胆囊切除术时偶然行阑尾切除术与单纯胆囊切除术治疗儿童的全国性结局:倾向评分匹配分析。

Nationwide outcomes of incidental appendectomy during cholecystectomy versus cholecystectomy alone in children: a propensity score-matched analysis.

机构信息

University of Miami Miller School of Medicine, Miami, FL, USA.

DeWitt Daughtry Family Department of Surgery, Division of Pediatric Surgery, University of Miami Leonard M. Miller School of Medicine, 1120 NW 14th Street, Suite 450K, Miami, FL, 33136, USA.

出版信息

Pediatr Surg Int. 2022 Oct;38(10):1413-1420. doi: 10.1007/s00383-022-05172-5. Epub 2022 Aug 3.

Abstract

BACKGROUND

The utility of incidental appendectomy, appendectomy during another index surgery in the absence of appendicitis, has not been evaluated in the pediatric population during cholecystectomy. This study sought to compare nationwide outcomes after cholecystectomy with incidental appendectomy in children.

METHODS

Patients ≤ 18 years old who underwent cholecystectomy from 2010-2014 were identified from the Nationwide Readmissions Database. A propensity score-matched analysis (PSMA) with > 40 covariates including demographics, comorbidities, and hospitalization factors was performed between those receiving cholecystectomy alone versus incidental appendectomy at the time of cholecystectomy.

RESULTS

34,390 patients underwent cholecystectomy (median age 15 [13-17] years). Laparoscopic (92%) approach was utilized most frequently, with 2% requiring conversion to open cholecystectomy. PSMA demonstrated a higher frequency of perforation or laceration of adjacent organs occurring in those receiving cholecystectomy alone during index admission. No significant differences in readmissions within 30 days or the calendar year were detected. Those undergoing cholecystectomy alone had higher overall readmission costs ($11,783 [$4942-$39,836] vs. $6,100 [$2358-$19,719] cholecystectomy with appendectomy; p = 0.010).

CONCLUSION

This nationwide PSMA indicates that incidental appendectomy in pediatric cholecystectomies is not associated with higher postoperative complications, cost, or readmissions. This suggests that incidental appendectomy during cholecystectomy is safe, cost-effective, and worthy of future study.

LEVEL OF EVIDENCE

Level III.

摘要

背景

在胆囊切除术中,对于无阑尾炎的偶然阑尾切除术或另一指数手术中的阑尾切除术的实用性,尚未在儿科人群中进行评估。本研究旨在比较儿童胆囊切除术中偶然阑尾切除术与非偶然阑尾切除术的全国范围结局。

方法

从 2010 年至 2014 年,从全国再入院数据库中确定了接受胆囊切除术的≤18 岁患者。对接受单纯胆囊切除术与在胆囊切除术时接受偶然阑尾切除术的患者进行了超过 40 个协变量(包括人口统计学、合并症和住院因素)的倾向评分匹配分析(PSMA)。

结果

34390 例患者接受了胆囊切除术(中位年龄为 15 岁[13-17 岁])。最常使用腹腔镜(92%)方法,有 2%需要转为开放性胆囊切除术。PSMA 显示,在指数住院期间接受单纯胆囊切除术的患者,相邻器官穿孔或撕裂的发生率更高。在 30 天或日历年内,未发现再入院率有显著差异。单纯行胆囊切除术的患者总再入院费用较高(11783 美元[4942-39836 美元] vs. 6100 美元[2358-19719 美元]行胆囊切除术+阑尾切除术;p=0.010)。

结论

这项全国性的 PSMA 表明,在小儿胆囊切除术时偶然阑尾切除术与术后并发症、成本或再入院率增加无关。这表明,在胆囊切除术中偶然行阑尾切除术是安全的、具有成本效益的,值得进一步研究。

证据等级

III 级。

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