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成人过敏性紫癜病例报告

A Case Report on an Adult Presentation of Henoch-Schönlein Purpura.

作者信息

Sood Raja, Parekh Priya, Raj Nitish, Saani Iqra

机构信息

Medicine, New Cross Hospital, Wolverhampton, GBR.

Otolaryngology, New Cross Hospital, Wolverhampton, GBR.

出版信息

Cureus. 2022 Jun 28;14(6):e26385. doi: 10.7759/cureus.26385. eCollection 2022 Jun.

Abstract

Henoch-Schönlein purpura (HSP) is an immunoglobulin A (IgA)-mediated multisystem vasculitis commonly affecting children under 10 years of age. Although diagnostic criteria exist, making a diagnosis is often difficult as this condition can present atypically in adults. We discuss a 22-year-old female with a delayed diagnosis of HSP, resulting in significant anxiety and distress. Our patient's symptoms improved with analgesia and corticosteroids, which were initiated upon diagnosis and she experienced two mild, self-limiting relapses over two years following symptom resolution. Our case illustrates that an integrated multidisciplinary approach is needed to effectively diagnose, safely manage and monitor patients presenting with HSP. Although self-limiting in nature, HSP has the potential to manifest into life-threatening conditions such as end-stage renal failure, which stresses the importance of early diagnosis and management.

摘要

过敏性紫癜(HSP)是一种由免疫球蛋白A(IgA)介导的多系统血管炎,常见于10岁以下儿童。尽管存在诊断标准,但由于这种疾病在成人中可能表现不典型,因此诊断往往很困难。我们讨论了一名22岁女性,其过敏性紫癜诊断延迟,导致严重焦虑和痛苦。我们的患者在诊断后开始使用镇痛药和皮质类固醇,症状得到改善,症状缓解后的两年内经历了两次轻微的、自限性复发。我们的病例表明,需要综合多学科方法来有效诊断、安全管理和监测患有过敏性紫癜的患者。尽管过敏性紫癜本质上是自限性的,但它有可能发展为危及生命的疾病,如终末期肾衰竭,这强调了早期诊断和管理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2594/9339340/ec74d9ee436a/cureus-0014-00000026385-i01.jpg

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