Waleed Muhammad, Perinkulam Sathyanarayanan Swaminathan, Arif Maan Soban, Mansoor Linta, Hoerschgen Kayla
Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, USA.
Internal Medicine: Diabetes and Endocrinology, Aga Khan University Hospital, Karachi, PAK.
Cureus. 2021 Nov 9;13(11):e19406. doi: 10.7759/cureus.19406. eCollection 2021 Nov.
Henoch-Schönlein purpura (HSP) is a self-limited vasculitis that affects children and the preadolescent population. It is characterized by the deposition of immunoglobulin A immune complexes in tissues leading to palpable purpura, abdominal pain, arthritis, and nephropathy. When it occurs in adults, the clinical manifestations are the same; however, adults present with more significant renal involvement. While abdominal pain is the most common gastrointestinal (GI) manifestation, it can also present with GI bleeding, intussusception, bowel ischemia, and bowel perforation. Here, we report the case of a 22-year-old gentleman who presented with nonspecific GI complaints such as nausea, vomiting, and loose stools. He was later found to have terminal ileitis preceding the onset of rash, the biopsy of which confirmed HSP. Terminal ileitis is a rare GI manifestation of HSP and is not very commonly reported in the literature.
过敏性紫癜（HSP）是一种影响儿童和青春期前人群的自限性血管炎。其特征是免疫球蛋白A免疫复合物在组织中沉积，导致可触及的紫癜、腹痛、关节炎和肾病。当它发生在成人身上时，临床表现相同；然而，成人的肾脏受累更为显著。虽然腹痛是最常见的胃肠道（GI）表现，但也可能出现胃肠道出血、肠套叠、肠缺血和肠穿孔。在此，我们报告一例22岁男性病例，该患者出现恶心、呕吐和腹泻等非特异性胃肠道症状。后来发现他在皮疹出现之前患有末端回肠炎，其活检证实为过敏性紫癜。末端回肠炎是过敏性紫癜罕见的胃肠道表现，在文献中报道并不常见。
