目前心力衰竭患者肌少症的诊断方法：临床和影像学评估作用的叙述性综述。
Current Approach to the Diagnosis of Sarcopenia in Heart Failure: A Narrative Review on the Role of Clinical and Imaging Assessments.
机构信息
Department of Internal Medicine (S.M.), Cleveland Clinic, OH.
Section of Musculoskeletal Imaging, Imaging Institute (B.L.E., P.-H.C.), Cleveland Clinic, OH.
出版信息
Circ Heart Fail. 2022 Oct;15(10):e009322. doi: 10.1161/CIRCHEARTFAILURE.121.009322. Epub 2022 Aug 4.
Abstract
Sarcopenia has been established as a predictor of poor outcomes in various clinical settings. It is particularly prevalent in heart failure, a clinical syndrome that poses significant challenges to health care worldwide. Despite this, sarcopenia remains overlooked and undertreated in cardiology practice. Understanding the currently proposed diagnostic process is paramount for the early detection and treatment of sarcopenia to mitigate downstream adverse health outcomes.
摘要
肌肉减少症已被确立为各种临床环境中不良预后的预测因子。它在心力衰竭中尤为普遍，心力衰竭是一种对全球医疗保健构成重大挑战的临床综合征。尽管如此，在心脏病学实践中，肌肉减少症仍然被忽视和治疗不足。了解目前提出的诊断流程对于早期发现和治疗肌肉减少症以减轻下游不良健康后果至关重要。
相似文献
1
Current Approach to the Diagnosis of Sarcopenia in Heart Failure: A Narrative Review on the Role of Clinical and Imaging Assessments.目前心力衰竭患者肌少症的诊断方法：临床和影像学评估作用的叙述性综述。
Circ Heart Fail. 2022 Oct;15(10):e009322. doi: 10.1161/CIRCHEARTFAILURE.121.009322. Epub 2022 Aug 4.
2
The challenge of frailty and sarcopenia in heart failure with preserved ejection fraction.射血分数保留的心力衰竭中衰弱和肌肉减少症的挑战。
Heart. 2017 Feb;103(3):184-189. doi: 10.1136/heartjnl-2016-309995. Epub 2016 Dec 9.
3
Sarcopenia and Frailty in Heart Failure: Is There a Biomarker Signature?肌肉减少症和心力衰竭中的虚弱：是否存在生物标志物特征？
Curr Heart Fail Rep. 2022 Dec;19(6):400-411. doi: 10.1007/s11897-022-00575-w. Epub 2022 Oct 20.
4
Exercise as a Therapeutic Strategy for Sarcopenia in Heart Failure: Insights into Underlying Mechanisms.运动作为心力衰竭性肌少症的治疗策略：潜在机制的研究进展。
Cells. 2020 Oct 13;9(10):2284. doi: 10.3390/cells9102284.
5
Sarcopenia, osteoporosis and frailty.肌肉减少症、骨质疏松症和衰弱。
Metabolism. 2023 Aug;145:155638. doi: 10.1016/j.metabol.2023.155638. Epub 2023 Jun 20.
6
Sex differences in the prevalence and prognostic impact of physical frailty and sarcopenia among older patients with heart failure.老年心力衰竭患者中身体虚弱和肌肉减少症的患病率和预后影响的性别差异。
Nutr Metab Cardiovasc Dis. 2022 Feb;32(2):365-372. doi: 10.1016/j.numecd.2021.10.012. Epub 2021 Oct 23.
7
New insights into the pathogenesis and treatment of sarcopenia in chronic heart failure.慢性心力衰竭中肌肉减少症发病机制和治疗的新见解。
Theranostics. 2019 May 31;9(14):4019-4029. doi: 10.7150/thno.33000. eCollection 2019.
8
Sarcopenia Trials in Specific Diseases: Report by the International Conference on Frailty and Sarcopenia Research Task Force.特定疾病中的肌肉减少症试验：衰弱与肌肉减少症研究国际会议特别工作组报告
J Frailty Aging. 2016;5(4):194-200. doi: 10.14283/jfa.2016.110.
9
Imaging of Sarcopenia.肌肉减少症的影像学评估
Radiol Clin North Am. 2022 Jul;60(4):575-582. doi: 10.1016/j.rcl.2022.03.001.
10
Association of CT-based diagnosis of sarcopenia with prognosis and treatment response in patients at risk of malnutrition - A secondary analysis of the Effect of early nutritional support on Frailty, Functional Outcomes, and Recovery of malnourished medical inpatients Trial (EFFORT) trial.基于 CT 的肌肉减少症诊断与营养不良风险患者的预后和治疗反应的相关性：早期营养支持对衰弱、功能结局和营养不良住院患者恢复的影响（EFFORT）试验的二次分析。
Clin Nutr. 2023 Feb;42(2):199-207. doi: 10.1016/j.clnu.2022.12.006. Epub 2022 Dec 22.
引用本文的文献
1
Impact of chest computed tomography-determined low skeletal muscle mass on the survival of patients with acute heart failure.胸部计算机断层扫描测定的低骨骼肌质量对急性心力衰竭患者生存的影响。
Front Cardiovasc Med. 2025 Aug 4;12:1569681. doi: 10.3389/fcvm.2025.1569681. eCollection 2025.
2
Multi-Organ Transplantation in Adult Congenital Heart Disease: Navigating the Unique Challenges of a Distinct Patient Population.成人先天性心脏病的多器官移植：应对特殊患者群体的独特挑战
Methodist Debakey Cardiovasc J. 2025 May 15;21(3):72-82. doi: 10.14797/mdcvj.1576. eCollection 2025.
3
Nutrition Optimization Among Critically Ill Patients in the Cardiac Intensive Care Unit.心脏重症监护病房重症患者的营养优化
Curr Cardiol Rep. 2025 Apr 4;27(1):79. doi: 10.1007/s11886-025-02208-9.
4
Skeletal muscle and subcutaneous fat quantity as prognostic indicators in cardiac amyloidosis.骨骼肌和皮下脂肪量作为心脏淀粉样变性的预后指标
Eur J Heart Fail. 2025 Jul;27(7):1294-1303. doi: 10.1002/ejhf.3622. Epub 2025 Feb 19.
5
Nutrition, dietary recommendations, and supplements for patients with congenital heart disease.先天性心脏病患者的营养、饮食建议及补充剂
Int J Cardiol Congenit Heart Dis. 2023 Mar 17;12:100449. doi: 10.1016/j.ijcchd.2023.100449. eCollection 2023 Jun.
6
Trajectory of health-related quality of life during and after hospitalisation due to worsening of heart failure.因心力衰竭恶化住院期间及出院后的健康相关生活质量轨迹。
Qual Life Res. 2025 Feb;34(2):471-484. doi: 10.1007/s11136-024-03818-6. Epub 2024 Oct 30.
7
Prognostic impact of muscle ultrasound-guided diagnosis of sarcopenia in older adults with severe aortic stenosis.肌肉超声引导下诊断肌肉减少症对重度主动脉瓣狭窄老年患者的预后影响
Eur Geriatr Med. 2024 Dec;15(6):1645-1656. doi: 10.1007/s41999-024-01042-6. Epub 2024 Sep 4.
8
Sarcopenia influences usage of reperfusion treatment in patients with pulmonary embolism aged 75 years and older.肌肉减少症影响75岁及以上肺栓塞患者再灌注治疗的使用情况。
Int J Cardiol Heart Vasc. 2024 Jul 19;53:101470. doi: 10.1016/j.ijcha.2024.101470. eCollection 2024 Aug.
9
Skeletal muscle quantity and quality evaluation in heart failure: comparing thoracic versus abdominopelvic CT approaches.评估心力衰竭患者的骨骼肌量和质：胸部 CT 与腹部 CT 方法的比较。
Int J Cardiovasc Imaging. 2024 Aug;40(8):1787-1796. doi: 10.1007/s10554-024-03169-w. Epub 2024 Jul 4.
10
Identifying the potential therapeutic effects of miR‑6516 on muscle disuse atrophy.鉴定 miR-6516 对肌肉废用性萎缩的潜在治疗作用。
Mol Med Rep. 2024 Jul;30(1). doi: 10.3892/mmr.2024.13243. Epub 2024 May 17.
本文引用的文献
1
Interventions for Frailty Among Older Adults With Cardiovascular Disease: JACC State-of-the-Art Review.老年心血管疾病患者衰弱的干预措施：JACC 现状评论。
J Am Coll Cardiol. 2022 Feb 8;79(5):482-503. doi: 10.1016/j.jacc.2021.11.029.
2
Increased estimated fat-free mass and fat mass associated with improved clinical outcome in heart failure.估计的去脂体重和脂肪量增加与心力衰竭临床结局改善相关。
Eur J Clin Invest. 2022 Jan;52(1):e13655. doi: 10.1111/eci.13655. Epub 2021 Aug 2.
3
Sarcopenia index as a predictor of clinical outcomes in older patients undergoing transcatheter aortic valve replacement.肌肉减少症指数作为老年经导管主动脉瓣置换术患者临床结局的预测指标
Catheter Cardiovasc Interv. 2021 Nov 15;98(6):E889-E896. doi: 10.1002/ccd.29799. Epub 2021 May 27.
4
Individualized Nutritional Support for Hospitalized Patients With Chronic Heart Failure.慢性心力衰竭住院患者的个体化营养支持。
J Am Coll Cardiol. 2021 May 11;77(18):2307-2319. doi: 10.1016/j.jacc.2021.03.232.
5
Skeletal muscle fat quantification by dual-energy computed tomography in comparison with 3T MR imaging.双能 CT 与 3T MRI 对骨骼肌脂肪定量的比较研究。
Eur Radiol. 2021 Oct;31(10):7529-7539. doi: 10.1007/s00330-021-07820-1. Epub 2021 Mar 26.
6
Can anthropometric measures be used as proxies for body composition and physical function in geriatric outpatients?人体测量指标可否作为老年门诊患者身体成分和身体功能的替代指标？
Arch Gerontol Geriatr. 2021 May-Jun;94:104379. doi: 10.1016/j.archger.2021.104379. Epub 2021 Feb 12.
7
Imaging Software-Based Sarcopenia Assessment in Gastroenterology: Evolution and Clinical Meaning.基于影像学的肌肉减少症评估在胃肠病学中的应用：演变和临床意义。
Can J Gastroenterol Hepatol. 2021 Jan 4;2021:6669480. doi: 10.1155/2021/6669480. eCollection 2021.
8
Radiologic Definition of Sarcopenia in Chronic Liver Disease.慢性肝病中肌肉减少症的放射学定义
Life (Basel). 2021 Jan 25;11(2):86. doi: 10.3390/life11020086.
9
Getting to grips with sarcopenia: recent advances and practical management for the gastroenterologist.认识肌肉减少症：胃肠病学家的最新进展与实际管理
Frontline Gastroenterol. 2020 Jan 20;12(1):53-61. doi: 10.1136/flgastro-2019-101348. eCollection 2021.
10
Muscle Composition Analysis of Ultrasound Images: A Narrative Review of Texture Analysis.超声图像肌肉成分分析：纹理分析的叙述性综述。
Ultrasound Med Biol. 2021 Apr;47(4):880-895. doi: 10.1016/j.ultrasmedbio.2020.12.012. Epub 2021 Jan 13.
Zotero 插件