一种来自中国南海软珊瑚的新型二十二烷型二萜类化合物。
A new capnosane-type diterpenoid from the South China sea soft coral .
作者信息
Zhang Di, Li Yueying, Li Xiaolei, Han Xiao, Wang Zhe, Li Guoqiang
机构信息
Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, People's Republic of China.
Department of Chemistry, Texas A&M University, College Station, Texas, USA.
出版信息
Nat Prod Res. 2024 Jan-Feb;38(1):97-102. doi: 10.1080/14786419.2022.2106568. Epub 2022 Aug 4.
A new rare capnosane-type diterpenoid () along with two known compounds sarcophyolides D () and arbolide C (), were isolated from the soft coral collected at Xisha Islands in the South China Sea. The structure of was established based on comprehensive spectroscopic data, literature comparison, and quantum chemical calculations. Compound exhibited moderate anti-inflammatory activities in the zebrafish model at a concentration of 20 μM.
从中国南海西沙群岛采集的软珊瑚中分离出一种新的罕见的癸烷型二萜（）以及两种已知化合物sarcophyolides D（）和arbolide C（）。基于综合光谱数据、文献比较和量子化学计算确定了的结构。化合物在斑马鱼模型中以20 μM的浓度表现出中等程度的抗炎活性。
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