Nadeem Syed Faisal, Baig Ahmer Nasir, Tariq Qurat Ul Ain, Shamim Muhammad Shahzad
Department of Neurosurgery, Medical College, The Aga Khan University, Karachi, Sindh, Pakistan.
Department of Neurosurgery, Aga Khan University Hospital, Karachi, Sindh, Pakistan.
Surg Neurol Int. 2022 Jul 15;13:299. doi: 10.25259/SNI_383_2022. eCollection 2022.
Arachnoiditis refers to chronic inflammation of the arachnoid mater and subarachnoid space due to three major etiologies: chemical, mechanical, and postinfectious. As a rare disease with variable symptomatology and severity at presentation, arachnoiditis can be extremely debilitating with many complications, prominent among which is syringomyelia.
We reviewed current literature concerning postinfectious spinal arachnoiditis and associated syringomyelia with emphasis on the treatment options that have been used to date and discuss their respective benefits and drawbacks.
It is critical to understand the natural history and potential complications of patient with postinfectious arachnoiditis. Surgical and medical treatments both have their own merits and demerits. Different surgical approaches have been employed with variable success rates.
At present, no consensus exists regarding management of these patients due to the variable nature of the disease that affects treatment efficacy; however, surgical intervention in selected cases may be beneficial.
蛛网膜炎是指由于化学、机械和感染后这三大病因导致的蛛网膜和蛛网膜下腔的慢性炎症。作为一种临床表现症状和严重程度各异的罕见疾病，蛛网膜炎会引发许多并发症，极其使人衰弱，其中最突出的是脊髓空洞症。
我们回顾了有关感染后脊髓蛛网膜炎及相关脊髓空洞症的当前文献，重点关注迄今为止所采用的治疗方案，并讨论它们各自的优缺点。
了解感染后蛛网膜炎患者的自然病程和潜在并发症至关重要。手术治疗和药物治疗都有其自身的优缺点。已采用了不同的手术方法，成功率各不相同。
目前，由于影响治疗效果的疾病性质多变，对于这些患者的管理尚无共识；然而，在某些选定病例中进行手术干预可能有益。
