Department of Medical Ethics, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Med Life. 2022 Jun;15(6):735-741. doi: 10.25122/jml-2021-0162.
Cord blood is a rich source of hematopoietic stem cells used to treat many diseases of blood origin. Thus, storage banks were created to store and provide umbilical cord cells. With the development of diagnostic and therapeutic technologies and techniques in medicine, ethical issues have also become more widespread and complex. After the creation of the cord blood banks, efforts were made to address the ethical issues associated with such banks. The present study attempts to identify the ethical challenges in these banks in the published studies. Databases including PubMed, Scopus, Web of Science (WOS), Embase, Proquest, and Google Scholar were searched from January 1996 to January 2021. Then, the ethical challenges of the cord blood bank were extracted from the results section using thematic content analysis. 22 studies were selected based on inclusion and exclusion criteria. The ethical challenges raised in the studies included private or public ownership of the bank, fair access to banking services, informed and voluntary consent, failure to provide sufficient information to individuals about the process, confidentiality of user's information, conflict of interest of bank founders (who are commonly doctors). The findings of this study indicated that there are serious ethical concerns regarding umbilical cord blood banks. Responding clearly to these ethical challenges calls for the attention of policymakers and medical ethics professionals; this will require a clear statement of the various aspects of these banks for society.
脐带血是一种丰富的造血干细胞来源,可用于治疗许多血液来源的疾病。因此,创建了存储库来存储和提供脐带细胞。随着医学诊断和治疗技术的发展,伦理问题也变得更加广泛和复杂。在创建脐带血库之后,人们努力解决与这些库相关的伦理问题。本研究试图在已发表的研究中确定这些银行的伦理挑战。从 1996 年 1 月至 2021 年 1 月,我们在 PubMed、Scopus、Web of Science(WOS)、Embase、Proquest 和 Google Scholar 等数据库中进行了搜索。然后,使用主题内容分析从结果部分提取脐带血库的伦理挑战。根据纳入和排除标准,选择了 22 项研究。研究中提出的伦理挑战包括银行的私人或公共所有权、公平获得银行服务、知情和自愿同意、未能向个人提供有关该过程的充分信息、用户信息的保密性、银行创始人(通常是医生)的利益冲突。本研究的结果表明,脐带血库存在严重的伦理问题。明确应对这些伦理挑战需要政策制定者和医学伦理专业人员的关注;这将需要为社会明确阐明这些银行的各个方面。