Gupta Deepika, Kaushal Manju, Jain Swasti
Department of Pathology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. RML Hospital, New Delhi, India.
Cytojournal. 2022 Jun 7;19:37. doi: 10.25259/Cytojournal_86_2020. eCollection 2022.
Xanthomas are papulonodular skin lesions present in lipoprotein metabolism disorders, which result in cholesterol deposits in subcutaneous tissue, tendons, ligaments, periosteum, etc. A 28-year-old male presented with multiple soft-tissue swellings, prominently over joints. Fine-needle aspiration (FNA) from multiple sites had similar appearance with foamy histocytes and giant cells. We describe an unusual case of tendinous and tuberous xanthoma diagnosed by cytology. Acquaintance with FNA cytology findings in xanthomas can help to avoid the need of surgical biopsy, as xanthomas can regress on medical therapy alone.
黄瘤是脂蛋白代谢紊乱时出现的丘疹结节性皮肤病变,可导致皮下组织、肌腱、韧带、骨膜等部位出现胆固醇沉积。一名28岁男性出现多处软组织肿胀,以关节部位最为明显。对多个部位进行细针穿刺抽吸(FNA),结果显示均有类似的泡沫状组织细胞和巨细胞。我们报告一例经细胞学诊断的肌腱和结节性黄瘤罕见病例。熟悉黄瘤的FNA细胞学检查结果有助于避免手术活检,因为黄瘤仅通过药物治疗即可消退。