Department of Neuroscience, Neuroradiological Unit, University of Turin, Azienda Ospedaliera Città della Salute e della Scienza Hospital, Turin, Italy.
Interv Neuroradiol. 2023 Oct;29(5):583-588. doi: 10.1177/15910199221118145. Epub 2022 Aug 4.
We herein report our experience with the 5F SOFIA (Soft Torqueable catheter Optimized for Intracranial Access) intermediate catheter for endovascular treatment of patients with acute ischemic stroke (AIS) both in distal middle vessel occlusions (DMVOs) and in large vessel occlusions (LVOs) with unfavorable anatomy.
Records of forty-seven patients undergoing endovascular thrombectomy with 5F SOFIA between September 2020 and March 2022 were retrospectively reviewed. Patients' demographic data, clinical presentation, treatment details, and complications were recorded from the medical record. The primary outcomes were successful revascularization (modified treatment in cerebral ischemia, mTICI ≥2b) and good clinical outcome at 3 months (modified rankin scale, mRS 0-2). Secondary outcomes were complication rates and switch to alternative techniques. Our institutional review board approved this study.
Forty-seven patients with AIS treated with 5F SOFIA were examined. In eighteen (38%) cases the occlusion was located on a large vessel while in 29 (61.7%) on a distal-medium vessels. Median national institutes of health strokes scale (NIHSS) score was 16 at admission. Successful revascularization to mTICI 2b-3 was achieved in 14 of 18 patients (77.7%) with LVOs and in 24/29 cases with DMVOs (82.7%) respectively. mRS score 0-2 at three months (3 months-mRS 0-2) was 66.6% for LVOs and 68.9% in DMVOs respectively. Symptomatic intracranial hemorrhage (SICH) occurred in 2 (4.2%) patients.
5F SOFIA intermediate catheter could be a safe and effective treatment for AIS and a viable alternative to 6 F conventional intermediate catheters in selected cases.
我们在此报告我们使用 5F SOFIA（用于颅内通路的软扭矩优化导管）中间导管对急性缺血性脑卒中（AIS）患者进行血管内治疗的经验，包括远端中等血管闭塞（DMVO）和大血管闭塞（LVO）伴不利解剖结构的患者。
回顾性分析 2020 年 9 月至 2022 年 3 月期间 47 例接受 5F SOFIA 血管内血栓切除术的患者记录。从病历中记录患者的人口统计学数据、临床表现、治疗细节和并发症。主要结局是血管再通成功（改良脑缺血治疗后血栓切除术，mTICI≥2b）和 3 个月时的良好临床结局（改良 Rankin 量表，mRS 0-2）。次要结局是并发症发生率和改用替代技术。我们的机构审查委员会批准了这项研究。
检查了 47 例 AIS 患者，用 5F SOFIA 治疗。18 例（38%）患者的闭塞位于大血管，29 例（61.7%）患者的闭塞位于远端-中等血管。入院时的中位国立卫生研究院卒中量表（NIHSS）评分为 16。18 例 LVO 患者中有 14 例（77.7%）和 29 例 DMVO 患者中有 24 例（82.7%）达到了 mTICI 2b-3 的再通。3 个月时 mRS 评分 0-2（3 个月-mRS 0-2）分别为 LVO 患者的 66.6%和 DMVO 患者的 68.9%。症状性颅内出血（SICH）发生在 2 例（4.2%）患者中。
5F SOFIA 中间导管可作为 AIS 的一种安全有效的治疗方法，在某些情况下是 6F 常规中间导管的可行替代方法。
