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腭裂修复术后的加速康复:一项质量改进项目。

Enhanced recovery after cleft palate repair: A quality improvement project.

机构信息

Division of Pediatric Anesthesiology, Department of Anesthesiology, Perioperative and Pain Medicine, Lucile Packard Children's Hospital Stanford, Stanford University School of Medicine, Palo Alto, California, USA.

Lucile Packard Children's Hospital Stanford, Plastic and Reconstructive Surgery, Cleft and Craniofacial Center, Palo Alto, California, USA.

出版信息

Paediatr Anaesth. 2022 Oct;32(10):1104-1112. doi: 10.1111/pan.14541. Epub 2022 Aug 11.

Abstract

BACKGROUND

Children undergoing cleft palate repair present challenges to postoperative management due to several factors that can complicate recovery. Utilization of multimodal analgesic protocols can improve outcomes in this population. We report experience designing and implementing an enhanced recovery after surgery (ERAS) pathway for cleft palate repair to optimize postoperative recovery.

AIMS

The primary aim was to implement an ERAS pathway with >70% bundle adherence to achieve a 30% reduction in postoperative opioid consumption within 12 months. Our secondary aims assessed intraoperative opioid consumption, length of stay, timeliness of oral intake, and respiratory recovery.

METHODS

A multidisciplinary team of perioperative providers developed an ERAS pathway for cleft palate patients. Key drivers included patient and provider education, formal pathway creation and implementation, multimodal pain therapy, and target-based care. Interventions included maxillary nerve blockade and enhanced intra- and postoperative medication regimens. Outcomes were displayed as statistical process control charts.

RESULTS

Pathway compliance was 77.0%. Patients during the intervention period (n = 39) experienced a 49% reduction in postoperative opioid consumption (p < .0001) relative to our historical cohort (n = 63), with a mean difference of -0.33 ± 0.11 mg/kg (95% CI -0.55 to -0.12 mg/kg). Intraoperative opioid consumption was reduced by 36% (p = .002), with a mean difference of -0.27 ± 0.09 mg/kg (95% CI -0.45 to -0.09 mg/kg). Additionally, patients in the intervention group had a 45% reduction in time to first oral intake (p = .02) relative to our historical cohort, with a mean difference of -3.81 ± 1.56 h (95% CI -6.9 to -0.70). There was no difference in PACU or hospital length of stay, but there was a significant reduction in variance of all secondary outcomes.

CONCLUSION

Opioid reduction and improved timeliness of oral intake is possible with an ERAS protocol for cleft palate repair, but our protocol did not alter PACU or hospital length of stay.

摘要

背景

由于多种因素可能使患儿腭裂修复术后的康复复杂化,因此接受腭裂修复术的儿童对术后管理提出了挑战。多模式镇痛方案的应用可以改善这类人群的预后。我们报告了设计和实施腭裂修复术后加速康复(ERAS)方案的经验,以优化术后恢复。

目的

主要目的是实施 ERAS 方案,使 70%以上的方案得到执行,以实现术后 12 个月内阿片类药物消耗减少 30%。我们的次要目标评估术中阿片类药物消耗、住院时间、口服摄入的及时性和呼吸恢复情况。

方法

围手术期多学科团队为腭裂患者制定了 ERAS 方案。主要驱动因素包括患者和医务人员的教育、正式的方案制定和实施、多模式疼痛治疗以及基于目标的护理。干预措施包括上颌神经阻滞和强化术中及术后药物治疗方案。结果以统计过程控制图显示。

结果

方案执行率为 77.0%。与我们的历史队列(n=63)相比,干预期间的患者(n=39)术后阿片类药物消耗减少了 49%(p<0.0001),平均差异为-0.33±0.11mg/kg(95%CI-0.55 至-0.12mg/kg)。术中阿片类药物消耗减少了 36%(p=0.002),平均差异为-0.27±0.09mg/kg(95%CI-0.45 至-0.09mg/kg)。此外,与历史队列相比,干预组患者首次口服摄入的时间减少了 45%(p=0.02),平均差异为-3.81±1.56h(95%CI-6.9 至-0.70h)。PACU 或住院时间无差异,但所有次要结局的方差均显著降低。

结论

腭裂修复术后加速康复方案可减少阿片类药物用量并提高口服摄入的及时性,但本方案并未改变 PACU 或住院时间。

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