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卤倍他索丙酸泡沫剂(0.05%)治疗青少年斑块状银屑病的评价性综述。

A critical review of halobetasol propionate foam (0.05%) as a treatment option for adolescent plaque psoriasis.

机构信息

Department of Dermatology, University of California, San Francisco, CA, USA.

出版信息

Expert Rev Clin Immunol. 2022 Oct;18(10):997-1003. doi: 10.1080/1744666X.2022.2110071. Epub 2022 Aug 8.

DOI:10.1080/1744666X.2022.2110071
PMID:35930002
Abstract

INTRODUCTION

Halobetasol propionate foam has been established as an efficacious and easy-to-use topical treatment for adults with plaque psoriasis. Its recent approval in the United States expanded its use for adolescents from ages 12 to 17 years old.

AREAS COVERED

We briefly summarize the chemistry of halobetasol and review clinical trials involving halobetasol propionate 0.05% foam to evaluate its efficacy and safety profile with a specific focus on adolescents with plaque psoriasis.

EXPERT OPINION

Halobetasol propionate 0.05% foam is an effective and cosmetically elegant superpotent topical corticosteroid, with a tolerable safety profile in adolescents. The use of this foam offers another option to address patient-specific needs and preferences, adding to the toolbox of currently available treatments for adolescent psoriasis.

摘要

简介

卤倍他索丙酸泡沫已被确立为一种治疗斑块状银屑病的有效且易于使用的外用药物。最近在美国的批准扩大了其在 12 至 17 岁青少年中的使用。

涵盖领域

我们简要总结了卤倍他索的化学性质,并回顾了涉及卤倍他索丙酸 0.05%泡沫的临床试验,以评估其疗效和安全性概况,特别关注斑块状银屑病的青少年患者。

专家意见

卤倍他索丙酸 0.05%泡沫是一种有效的、美容优雅的超强效外用皮质类固醇,在青少年中具有可耐受的安全性。这种泡沫的使用为满足特定患者的需求和偏好提供了另一种选择,为青少年银屑病的现有治疗方法增添了一种新的选择。

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