Fedorova E N, Boĭkov V P, Filippova N A
Arkh Patol. 1987;49(3):69-73.
Laryngeal carcinoid with metastases to cervical lymph nodes was observed in a patient of 62. The diagnosis was confirmed by electron-microscopic study. The patient was followed up for 9 mos without any evidence of recurrence and metastases after laryngectomy and fascial envelope excision of cervical fat. The morphologic picture of laryngeal carcinoid is characterized by the presence of the alveolar, trabecular and teniform structures consisting of monomorphic and moderately polymorphic cells. Tubular and rosette-like structures occur. The overlying epithelium is intact. The necrotic foci, as a rule, are absent. Grimelius reaction is positive, argentaffinnic granularity isn't revealed. Electron-microscopic study demonstrates endocrine-type granules. The need for recognition of laryngeal carcinoid is explained by the fact that this tumour form has a more favourable course and prognosis in comparison to cancer.
一名62岁患者被发现患有喉类癌并伴有颈部淋巴结转移。诊断通过电子显微镜研究得以证实。患者在接受喉切除术及颈部脂肪筋膜包膜切除术后接受了9个月的随访，未发现任何复发和转移迹象。喉类癌的形态学特征表现为存在由单形性和中度多形性细胞组成的肺泡状、小梁状和条索状结构。可见管状和玫瑰花结样结构。覆盖上皮完整。通常无坏死灶。嗜银反应呈阳性，未显示嗜银颗粒。电子显微镜研究显示内分泌型颗粒。认识喉类癌的必要性在于，与癌症相比，这种肿瘤形式的病程和预后更有利。
