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COVID-19 相关长期骨科表现:异位骨化和指(趾)干性坏死。

Long-term Orthopedic Manifestations of COVID-19: Heterotopic Ossification and Digital Necrosis.

机构信息

Department of Orthopaedics, Warren Alpert Medical School of Brown University, Providence, Rhode Island.

Department of Orthopaedics, Warren Alpert Medical School of Brown University; University Orthopedics, Inc., Providence, RI.

出版信息

R I Med J (2013). 2022 Sep 1;105(7):31-35.

PMID:35930488
Abstract

Despite its classification as an atypical pneumonia, COVID-19 is a disease that is capable of inflicting damage beyond the respiratory system. The wide range of musculoskeletal complications secondary to acute COVID-19 are a significant source of morbidity in hospitalized patients. We present the case of a 23-year-old woman with severe COVID-19 who required intubation and had a prolonged hospital course that was complicated by partial-thickness necrosis of her fingers and heterotopic ossification of the distal thigh. We review current treatments for these orthopedic conditions in the setting of SARS-CoV-2 infection as well as highlight areas for future research. Additionally, we discuss the subacute musculoskeletal complications of COVID-19, which are among the most common long-term manifestations of the disease and are increasingly important for a growing number of COVID-19 survivors.

摘要

尽管 COVID-19 被归类为一种非典型性肺炎,但它是一种能够对呼吸系统以外的器官造成损害的疾病。急性 COVID-19 引发的广泛的肌肉骨骼并发症是住院患者发病率的一个重要来源。我们报告了一例 23 岁的重症 COVID-19 女性患者,她需要插管,并且住院时间延长,手指出现部分厚度坏死,大腿远端出现异位骨化。我们回顾了 SARS-CoV-2 感染背景下这些骨科疾病的当前治疗方法,并强调了未来研究的领域。此外,我们还讨论了 COVID-19 的亚急性肌肉骨骼并发症,这些并发症是该疾病最常见的长期表现之一,对于越来越多的 COVID-19 幸存者来说,这些并发症变得越来越重要。

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Heterotopic ossification following COVID-19 infections: systematic literature review of case reports and case series.COVID-19 感染后异位骨化:病例报告和病例系列的系统文献回顾。
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