Morris H H, Estes M L, Lüders H, Lesser R P, Dinner D S, Hahn J, Wyllie E
Arch Neurol. 1987 Jul;44(7):703-8. doi: 10.1001/archneur.1987.00520190015009.
We studied interictal activity and site of ictal onset in 26 patients with complex partial seizures of temporal lobe origin. All patients had prolonged electrocorticographic recordings from subdural electrode arrays placed both over the convexity and beneath the temporal lobe. We found a significant correlation between the epileptogenic focus and the type of pathologic lesion found at time of surgery. Macroscopic lesions strongly tended to have an epileptogenic focus on the lateral surface of the temporal lobe; patients with only microscopic abnormalities tended to have an epileptogenic focus in the mesial/basal region of the temporal lobe.
我们研究了26例颞叶起源的复杂部分性发作患者的发作间期活动和发作起始部位。所有患者均通过置于脑凸面和颞叶下方的硬膜下电极阵列进行了长时间的皮质电图记录。我们发现癫痫病灶与手术时发现的病理病变类型之间存在显著相关性。宏观病变强烈倾向于在颞叶外侧表面有癫痫病灶；仅存在微观异常的患者倾向于在颞叶内侧/基底区域有癫痫病灶。
