Sarpel G, Chaudry F, Hindo W
Arch Neurol. 1987 Jul;44(7):725-8. doi: 10.1001/archneur.1987.00520190035014.
Using a beta-permanent magnet (Fonar 3000), we evaluated magnetic resonance imaging of periventricular hyperintensity (PVH) patterns in 60 patients (59 white, 58 men) from the Veterans Administration Hospital, North Chicago, Ill. Eighty percent of the patients had evidence of PVH, which increased significantly in patients older than age 50 years. In addition to age, history of atherosclerotic cardiovascular disease and extracranial malignancy showed a significant association with PVH. A linear correlation was observed between the severity of PVH and an abnormal neurologic examination. In this retrospective, uncontrolled study, we concluded that PVH incidence among white men is high and increases with age or the presence of cardiovascular disease or extracranial malignancy. The degree of PVH positively correlates with abnormal neurologic evaluation and additional abnormalities seen on magnetic resonance imaging. However, the disease-related specificity is as yet undetermined.
我们使用一台贝塔永久磁铁（Fonar 3000），对伊利诺伊州北芝加哥退伍军人管理局医院的60名患者（59名白人，58名男性）的脑室周围高信号（PVH）模式进行了磁共振成像评估。80%的患者有PVH证据，在50岁以上的患者中PVH显著增加。除年龄外，动脉粥样硬化性心血管疾病史和颅外恶性肿瘤与PVH也有显著关联。PVH的严重程度与神经系统检查异常之间存在线性相关性。在这项回顾性、非对照研究中，我们得出结论，白人男性中PVH的发病率很高，且随年龄增长或存在心血管疾病或颅外恶性肿瘤而增加。PVH的程度与神经系统评估异常以及磁共振成像上发现的其他异常呈正相关。然而，与疾病相关的特异性尚未确定。
