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家庭传播的 A 组链球菌坏死性筋膜炎。

Household Transmission of Group A Streptococcus Necrotizing Fasciitis.

机构信息

From the Department of Orthopaedic Surgery (Dr. Markowitz, Dr. Kwan), Rowan University SOM, Stratford, NJ (Dr. Markowitz, Dr. Kwan), and Orthopaedic Surgery (Dr. Matzon), Rothman Orthopaedic Institute-Hand, Wrist, Elbow, & Microvascular Surgery, Sidney Kimmel Medical College at Thomas Jefferson University, Rothman Institute, Philadelphia, PA.

出版信息

J Am Acad Orthop Surg Glob Res Rev. 2022 Aug 3;6(8). doi: 10.5435/JAAOSGlobal-D-21-00171. eCollection 2022 Aug 1.

DOI:10.5435/JAAOSGlobal-D-21-00171
PMID:35930803
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9351906/
Abstract

A healthy 40-year-old woman was diagnosed with necrotizing fasciitis 2 days after her husband's death from the same infectious process. Prompt identification and immediate surgical intervention prevented a similar result in this patient. Additional investigation into both patients' medical records found the inciting organism to be group A streptococcus. Although the exact mechanism of inoculation is unknown, the spread of this infection within a household prompts the question of whether antibiotic prophylaxis should be given among close contacts in future cases of necrotizing fasciitis.

摘要

一名健康的 40 岁女性在其丈夫因相同感染过程去世两天后被诊断患有坏死性筋膜炎。及时识别并立即进行手术干预,避免了该患者出现类似结果。对两名患者的病历进行进一步调查发现,引发感染的病原体为 A 组链球菌。虽然接种的确切机制尚不清楚,但这种感染在家庭内传播,促使人们提出在未来的坏死性筋膜炎病例中,是否应给予密切接触者抗生素预防的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5281/9351906/b4c60e3810e6/jagrr-6-e21.00171-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5281/9351906/f8712caf7a38/jagrr-6-e21.00171-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5281/9351906/b3ec2ac798e5/jagrr-6-e21.00171-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5281/9351906/b4c60e3810e6/jagrr-6-e21.00171-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5281/9351906/f8712caf7a38/jagrr-6-e21.00171-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5281/9351906/b3ec2ac798e5/jagrr-6-e21.00171-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5281/9351906/b4c60e3810e6/jagrr-6-e21.00171-g003.jpg

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本文引用的文献

1
Necrotizing Soft-Tissue Infections.坏死性软组织感染
N Engl J Med. 2018 Mar 8;378(10):971. doi: 10.1056/NEJMc1800049.
2
Familial Transmission of emm12 Group A Streptococcus.emm12 组 A 链球菌的家族传播。
Emerg Infect Dis. 2017 Oct;23(10):1745-1746. doi: 10.3201/eid2310.170343.
3
Management of Contacts of Patients With Severe Invasive Group A Streptococcal Infection.严重侵袭性A组链球菌感染患者接触者的管理
J Pediatric Infect Dis Soc. 2016 Mar;5(1):47-52. doi: 10.1093/jpids/piu107. Epub 2014 Oct 30.
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Early diagnosis of necrotizing fasciitis.早期诊断坏死性筋膜炎。
Br J Surg. 2014 Jan;101(1):e119-25. doi: 10.1002/bjs.9371. Epub 2013 Nov 29.
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Necrotizing fasciitis.坏死性筋膜炎
J Am Acad Orthop Surg. 2009 Mar;17(3):174-82. doi: 10.5435/00124635-200903000-00006.
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Necrotizing fasciitis: current concepts and review of the literature.坏死性筋膜炎:当前概念及文献综述
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Invasive group A streptococcal disease: should close contacts routinely receive antibiotic prophylaxis?侵袭性A组链球菌病:密切接触者是否应常规接受抗生素预防?
Lancet Infect Dis. 2005 Aug;5(8):494-500. doi: 10.1016/S1473-3099(05)70190-0.
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Necrotizing fasciitis: pathogenesis and treatment.坏死性筋膜炎:发病机制与治疗
Expert Rev Anti Infect Ther. 2005 Apr;3(2):279-94. doi: 10.1586/14787210.3.2.279.
9
The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections.LRINEC(坏死性筋膜炎实验室风险指标)评分:一种区分坏死性筋膜炎与其他软组织感染的工具。
Crit Care Med. 2004 Jul;32(7):1535-41. doi: 10.1097/01.ccm.0000129486.35458.7d.
10
Household transmission of invasive group A streptococcus with necrotizing fasciitis.侵袭性A组链球菌伴坏死性筋膜炎的家庭传播
Scand J Infect Dis. 2003;35(6-7):414-5. doi: 10.1080/00365540310010967.