Fujita M, Koike Y
Auris Nasus Larynx. 1986;13(3):129-38. doi: 10.1016/s0385-8146(86)80009-8.
A "Crib-O-Gram" was employed for an automatic screening of hearing impaired newborns. A series of 502 neonates were tested, and 57 babies were judged to be "REFER." These "REFER'd" subjects were further examined with ABR, and 4 hearing impaired subjects were found. A detailed history was available in 427 neonates, and "risk factors" related to hearing impairment were investigated. The incidence of "REFER" judgment was found to be significantly higher for the group of neonates with risk factors than for those without risk factors. The rate of "REFER" judgment was computed for each risk factor, and the phi-coefficient of association was calculated to study the statistical relationship between the "REFER" judgment and each risk factor. A significant relationship was confirmed for anatomic malformations, positive family history of deafness, and congenital perinatal infection. The relationship between the existence of hearing impairment and each risk factor was similarly studied. Congenital perinatal infection and family history of deafness were significantly associated with hearing impairment, although anatomic malformation was not significantly related. The quantification theory (Hayashi type II) was applied to calculate a relative weight of each risk factor in reference to both the REFER judgment and hearing impairment. It was pointed out that proper weighting of each risk factor may be useful in improving the efficiency of screening.
采用“婴儿听力筛查图”对听力受损新生儿进行自动筛查。对502名新生儿进行了测试，57名婴儿被判定为“需进一步检查”。对这些“需进一步检查”的对象进行了听性脑干反应（ABR）复查，发现4名听力受损对象。有427名新生儿有详细病史，对与听力损害相关的“危险因素”进行了调查。发现有危险因素的新生儿组“需进一步检查”判定的发生率显著高于无危险因素的新生儿组。计算了每个危险因素的“需进一步检查”判定率，并计算了关联的phi系数，以研究“需进一步检查”判定与每个危险因素之间的统计关系。证实解剖畸形、耳聋家族史阳性和先天性围产期感染之间存在显著关系。同样研究了听力损害的存在与每个危险因素之间的关系。先天性围产期感染和耳聋家族史与听力损害显著相关，尽管解剖畸形与之无显著关系。应用量化理论（林氏II型）计算每个危险因素相对于“需进一步检查”判定和听力损害的相对权重。指出对每个危险因素进行适当加权可能有助于提高筛查效率。
