Department of Anaesthesiology, Lady Hardinge Medical College, New Delhi, India.
J Coll Physicians Surg Pak. 2022 Aug;32(8):1086-1088. doi: 10.29271/jcpsp.2022.08.1086.
Opsoclonus-myoclonus syndrome (OMS) or the dancing eye syndrome, is a rare inflammatory neurological disorder often with paraneoplastic aetiology. It has an incidence of 1 in 1000,000 population worldwide. Opsoclonus-myoclonus syndrome is associated with 2-3% of patients having neuroblastoma. The authors present 5 cases of OMS in children who had neuroblastoma and underwent surgical resection. The median age was 26 (14-36) months. Male: female ratio was 1:1.5. All the patients had moderate to severe symptoms. Duration of symptoms at presentation varied from 3 days to one and half years. The possibility of OMS should be considered in all children presenting with probable neurological symptoms. Pharmacological therapy combined with surgery results in a good outcome. Balanced anaesthesia with the most commonly used drugs can be safely administered in the patients with opsoclonus-myoclonus syndrome. Key Words: Opsoclonus, Myoclonus, Neuroblastoma, Child, Anaesthesia.
眼-口-肌阵挛综合征（OMS）或舞蹈眼综合征，是一种罕见的炎症性神经疾病，常伴有副肿瘤病因。其全球发病率为 1/1000000。眼-口-肌阵挛综合征与 2-3%的神经母细胞瘤患者有关。作者报告了 5 例患有神经母细胞瘤并接受手术切除的儿童 OMS 病例。中位年龄为 26（14-36）个月。男女比例为 1:1.5。所有患者均有中度至重度症状。就诊时症状持续时间从 3 天到 1 年半不等。所有出现可能神经症状的儿童均应考虑 OMS 的可能性。药物治疗联合手术可获得良好的结果。在眼-口-肌阵挛综合征患者中，可以安全地给予最常用药物的平衡麻醉。关键词：眼-口-肌阵挛，肌阵挛，神经母细胞瘤，儿童，麻醉。
