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脊柱融合术后新发痴呆症的发病率和医疗保健利用情况:倾向评分匹配分析。

Incidence of new onset dementia and health care utilization following spine fusions: A propensity score matching analysis.

机构信息

Department of Neurosurgery, University of Louisville, 200 Abraham Flexner Hwy, Louisville, KY 40202, USA.

Department of Orthopedics, Boston University Medical Center, Boston, MA 02118, USA.

出版信息

Neurochirurgie. 2022 Dec;68(6):562-568. doi: 10.1016/j.neuchi.2022.07.010. Epub 2022 Aug 3.

DOI:10.1016/j.neuchi.2022.07.010
PMID:35932885
Abstract

BACKGROUND

Dementia following spine fusions is not described in the literature. Also, the impact of new onset dementia on long-term health care utilization is not described. The aim of our study was to define the incidence of new onset dementia and its long-term health care utilization in elderly patients.

MATERIALS AND METHODS

MarketScan database were queried using the ICD-9/10 and CPT 4th edition, from 2001 to 2019. We included patients≥55 of age who underwent spine fusions with at least 5years follow-up. Outcomes were new onset dementia (>6months after the procedure) length of stay (LOS), discharge disposition, hospital readmissions, outpatient services, and medication refills.

RESULTS

Of 45,129 patients who underwent spine fusions, 1283 patients (2.84%) were diagnosed to have new onset dementia. There was no difference in the reoperation rates among the dementia and non-dementia cohort at 1-, 2- and 5-years following the index procedure. Patients in the dementia cohort incurred higher number of hospital readmissions up to 5-years after the index procedure. In terms of combined index procedure and post-discharge utilization payments, significant differences were noted among the dementia vs. non-dementia cohorts at 5-years ($126,628 vs. $77,098), following the index procedure.

CONCLUSION

Elderly age, higher comorbidities, Medicare insurance, multilevel lumbosacral fusions were identified as risk markers for developing dementia following spine fusions. Dementia resulted in significantly higher health care utilization with no increased rate of reoperations for up to 5-years following the index procedure.

摘要

背景

文献中并未描述脊柱融合术后的痴呆症。此外,新发痴呆症对长期医疗保健利用的影响也尚未可知。我们的研究目的是确定老年患者脊柱融合术后新发痴呆症的发生率及其长期医疗保健利用情况。

材料与方法

使用 ICD-9/10 和 CPT 第 4 版,从 2001 年到 2019 年,在 MarketScan 数据库中进行了查询。我们纳入了年龄≥55 岁且至少有 5 年随访的接受脊柱融合术的患者。主要结局为新发痴呆症(手术 6 个月后)、住院时间(LOS)、出院去向、医院再入院、门诊服务和药物续配。

结果

在接受脊柱融合术的 45129 例患者中,有 1283 例(2.84%)被诊断为新发痴呆症。在指数手术后 1、2 和 5 年,痴呆组和非痴呆组的再手术率没有差异。痴呆组患者在指数手术后 5 年内的住院再入院次数更多。在指数手术和出院后利用支付的综合指标方面,痴呆组与非痴呆组在 5 年内的差异显著(126628 美元 vs. 77098 美元)。

结论

年龄较大、合并症较多、医疗保险、多节段腰骶部融合术被认为是脊柱融合术后发生痴呆症的风险标志物。痴呆症导致了更高的医疗保健利用,且指数手术后 5 年内的再手术率并未增加。

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