Department of Neurosurgery, University of Louisville, 200 Abraham Flexner Hwy, Louisville, KY 40202, USA.
Evergreen Hospital Neuroscience Institute, Kirkland, WA 98034, USA.
J Clin Neurosci. 2021 Nov;93:122-129. doi: 10.1016/j.jocn.2021.09.024. Epub 2021 Sep 17.
Identify the impact of preoperative treatment of Osteoporosis (OP) on reoperation rates, complications and healthcare utilization following thoraco-lumbar (TL) spine fusions.
We used ICD9/10 and CPT codes to extract data from MarketScan (2000-2018). Patients were divided into two groups based on preoperative treatment of OP within one year prior to the index spinal fusion: medication (m-OP) cohort and non-medication (nm-OP) cohort. Outcomes (re-operation rates, re-admission, complications, healthcare utilization) were analyzed at 1-, 12-, 24- and 60-months.
Of 3606 patients, 65% (n = 2330) of patients did not receive OP medications (nm-OP). At index hospitalization, there were no difference in LOS (median nm-OP: 3 days vs. m-OP:4 days), discharge to home (nm-OP 80% vs. m-OP 75%) and complications (nm-OP 13% vs. m-OP 12%). Reoperation rates were not different among the cohorts at 1- (nm-OP 5.7% vs. m-OP 4.2%), 2- (nm-OP 9.4% vs. m-OP 7.8) and 5 years (nm-OP 16.9% vs. m-OP 14.8%). Patients in m-OP cohort incurred higher overall median payments at 1 year ($17,866 vs. $ 16,010), 2 years ($38,634 vs. $34,454) and 5 years ($94,797 vs. $91,072) compared to nm-OP cohort.
Preoperative treatment of OP had no impact on complications, LOS, discharge disposition following TL fusions at index hospitalization. Similarly, no impact of preoperative treatment was noted in terms of reoperation rates at 12-, 24- and 60 months following the index spine fusion. Patients who received preoperative treatment for OP incurred higher health care utilization at 12-, 24- and 60 months following surgery.
确定术前骨质疏松(OP)治疗对胸腰椎(TL)脊柱融合术后再手术率、并发症和医疗保健利用的影响。
我们使用 ICD9/10 和 CPT 代码从 MarketScan(2000-2018 年)中提取数据。根据索引脊柱融合术前一年内在 OP 进行的术前治疗,将患者分为两组:药物(m-OP)组和非药物(nm-OP)组。在 1、12、24 和 60 个月时分析结果(再手术率、再入院、并发症、医疗保健利用)。
在 3606 名患者中,65%(n=2330)的患者未接受 OP 药物治疗(nm-OP)。在索引住院期间, LOS(nm-OP 中位数:3 天 vs. m-OP:4 天)、出院回家(nm-OP 80% vs. m-OP 75%)和并发症(nm-OP 13% vs. m-OP 12%)无差异。在 cohorts 中,1 年(nm-OP 5.7% vs. m-OP 4.2%)、2 年(nm-OP 9.4% vs. m-OP 7.8%)和 5 年(nm-OP 16.9% vs. m-OP 14.8%)的再手术率无差异。m-OP 队列的患者在 1 年($17866 比 $16010)、2 年($38634 比 $34454)和 5 年($94797 比 $91072)的总中位数支付更高。
TL 融合术前 OP 治疗对 TL 融合术后的并发症、LOS、索引住院期间的出院处置没有影响。同样,在索引脊柱融合术后 12、24 和 60 个月时,术前治疗对再手术率也没有影响。接受 OP 术前治疗的患者在手术后 12、24 和 60 个月时的医疗保健利用率更高。