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产碳青霉烯酶肺炎克雷伯菌致神经外科术后感染 1 例并文献复习

A Post-Neurosurgical Infection due to KPC-Producing Klebsiella pneumoniae Treated with Meropenem-Vaborbactam: A Case Report.

机构信息

School of Pharmacy, University of Washington, Seattle, USA.

Melinta Therapeutics, Morristown, USA.

出版信息

Int J Infect Dis. 2022 Sep;122:1041-1043. doi: 10.1016/j.ijid.2022.07.073. Epub 2022 Aug 3.

DOI:10.1016/j.ijid.2022.07.073
PMID:35932967
Abstract

This case report describes a patient with post-neurosurgical infection and bacteremia caused by Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae. There is limited evidence to guide antibiotic treatment decisions for such infections. The patient was treated with meropenem-vaborbactam (MEV). MEV monotherapy was associated with bacteremia clearance.

摘要

本病例报告描述了一例神经外科手术后感染和血流感染的患者，感染由产碳青霉烯酶肺炎克雷伯菌引起。对于此类感染，抗生素治疗决策的指导证据有限。患者接受了美罗培南-维巴坦（MEV）治疗。MEV 单药治疗与菌血症清除相关。

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