Department of Endocrinology, Key Laboratory of Endocrinology, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Department of Cardiac Intensive Care Unit, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Eur J Med Res. 2022 Aug 8;27(1):144. doi: 10.1186/s40001-022-00774-0.
To assess changes in bone mineral density (BMD) following bariatric surgery (BS) in patients with different bone sites, postoperative periods and ages. Twenty-two studies were included. Femoral neck (FN) BMD decreased after surgery (MD, - 0.05 g/cm, CI - 0.10 to - 0.01, P = 0.03). Postoperative BMD decreased more in the FN and lumbar spine (LS) of patients older than 40 (FNBMD, - 0.07 g/cm, CI - 0.13 to - 0.00, P = 0.04; LSBMD, - 0.03 g/cm, CI - 0.05 to - 0.00, P = 0.02) or patients with a postoperative time of greater than 12 months (FNBMD, - 0.06 g/cm, CI - 0.12 to - 0.01, P = 0.03; LSMD, - 0.04 g/cm, CI - 0.09 to 0.01, P = 0.12); therefore, post-BS bone loss should be monitored among patients in these groups. Longer follow-ups are needed to determine whether BMD changes or stabilizes.
评估不同骨部位、术后时期和年龄的患者在接受减重手术后（BS）骨密度（BMD）的变化。共纳入 22 项研究。术后股骨颈（FN）BMD 降低（MD，-0.05g/cm，CI-0.10 至-0.01，P=0.03）。40 岁以上患者的 FN 和腰椎（LS）的术后 BMD 下降更多（FNBMD，-0.07g/cm，CI-0.13 至-0.00，P=0.04；LSBMD，-0.03g/cm，CI-0.05 至-0.00，P=0.02）或术后时间大于 12 个月的患者（FNBMD，-0.06g/cm，CI-0.12 至-0.01，P=0.03；LSBMD，-0.04g/cm，CI-0.09 至 0.01，P=0.12）；因此，应监测这些患者群体的术后骨丢失情况。需要更长时间的随访来确定 BMD 是否发生变化或稳定。
