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经导管主动脉瓣植入术后永久起搏器植入患者的房室传导:使用文氏点测量的意义

Atrioventricular conduction in PM recipients after transcatheter aortic valve implantation: Implications using Wenckebach point measurement.

作者信息

Pelargonio Gemma, Scacciavillani Roberto, Donisi Luca, Narducci Maria Lucia, Aurigemma Cristina, Pinnacchio Gaetano, Bencardino Gianluigi, Perna Francesco, Spera Francesco Raffaele, Comerci Gianluca, Ruscio Eleonora, Romagnoli Enrico, Crea Filippo, Burzotta Francesco, Trani Carlo

机构信息

Department of Cardiovascular Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

Cardiology Institute, Catholic University of Sacred Heart, Rome, Italy.

出版信息

Front Cardiovasc Med. 2022 Jul 22;9:904828. doi: 10.3389/fcvm.2022.904828. eCollection 2022.

Abstract

BACKGROUND

Atrioventricular (AV) conduction disturbances requiring permanent pacemaker implantation (PPI) are a common complication after transcatheter aortic valve implantation (TAVI). However, a significant proportion of patients might recover AV conduction at follow-up.

OBJECTIVES

The aim of our study was to evaluate the recovery of AV conduction by determination through Wenckebach point in patients with PPI and therefore identify patients who could benefit from device reprogramming to avoid unnecessary RV pacing.

METHODS

We enrolled 43 patients that underwent PM implantation after TAVI at our Department from January 2018 to January 2021. PM interrogation was performed at follow-up and patients with native spontaneous rhythm were further assessed for AV conduction through WP determination.

RESULTS

A total of 43 patients requiring a PM represented the final study population, divided in patients with severely impaired AV conduction (no spontaneous valid rhythm or WP < 100; 26) and patients with valid AV conduction (WP ≥ 100; 17). In the first group patients had a significantly higher number of intraprocedural atrioventricular block (AVB) (20 vs. 1, < 0.005), showed a significant higher implantation depth in LVOT (7.7 ± 2.2 vs. 4.4 ± 1.1, < 0.05) and lower ΔMSID (-0.28 ± 3 vs. -3.94 ± 2, < 0.05).

CONCLUSION

AV conduction may recover in a significant proportion of patients. In our study, valve implantation depth in the LVOT and intraprocedural AV block are associated with severely impaired AV conduction. Regular PM interrogation and reprogramming are required to avoid unnecessary permanent right ventricular stimulation in patients with AV conduction recovery.

摘要

背景

需要植入永久起搏器(PPI)的房室传导障碍是经导管主动脉瓣植入术(TAVI)后的常见并发症。然而,相当一部分患者在随访时可能恢复房室传导。

目的

我们研究的目的是通过测定文氏点来评估植入永久起搏器患者的房室传导恢复情况,从而识别那些可从设备重新编程中获益以避免不必要右室起搏的患者。

方法

我们纳入了2018年1月至2021年1月在我院接受TAVI后植入起搏器的43例患者。随访时进行起搏器程控,对有自身窦性心律的患者通过测定文氏点进一步评估房室传导。

结果

总共43例需要植入起搏器的患者构成最终研究人群,分为房室传导严重受损(无自发有效心律或文氏点<100;26例)和房室传导有效(文氏点≥100;17例)的患者。第一组患者术中房室传导阻滞(AVB)的发生率显著更高(20例 vs. 1例,<0.005),左室流出道(LVOT)的植入深度显著更深(7.7±2.2 vs. 4.4±1.1,<0.05),且MSID差值更低(-0.28±3 vs. -3.94±2,<0.05)。

结论

相当一部分患者的房室传导可能恢复。在我们的研究中,LVOT的瓣膜植入深度和术中AVB与房室传导严重受损相关。对于房室传导恢复的患者,需要定期进行起搏器程控和重新编程以避免不必要的永久性右室刺激。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cff6/9353552/ef1868f918d5/fcvm-09-904828-g001.jpg

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