• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

埃文斯综合征表现为新型冠状病毒疫苗接种的非典型并发症。

Evans Syndrome Presenting as an Atypical Complication of SARS-CoV-2 Vaccination.

作者信息

De Felice Marco, Farina Giuliana, Bianco Rosario, Monaco Giuseppe, Iaccarino Salvatore

机构信息

Hematology and Medical Oncology, AORN Sant'Anna and San Sebastiano, Caserta, ITA.

Clinical Oncology, Università degli Studi della Campania "Luigi Vanvitelli", Naples, ITA.

出版信息

Cureus. 2022 Jul 6;14(7):e26602. doi: 10.7759/cureus.26602. eCollection 2022 Jul.

DOI:10.7759/cureus.26602
PMID:35936148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9354064/
Abstract

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has drastically affected our daily lives, causing millions of deaths worldwide. The early and late complications of this infection are being increasingly revealed on a regular basis; however, an important brake on the spread and especially the lethality of the disease has been guaranteed by the introduction of mRNA-based and viral vector-based COVID-19 Vaccines. Also, an increasing number of adverse effects of the vaccination have been reported to specific pharmacovigilance boards, most of them totally non-serious events that are resolved within one to three days after the administration of the vaccine. In this report, we present a case of Evans syndrome (ES) secondary to SARS-CoV-2 vaccination in an 85-year-old male patient. To the best of our knowledge, this is the first case of ES caused by the COVID-19 vaccination to be reported in the literature.

摘要

由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的2019冠状病毒病(COVID-19)大流行,极大地影响了我们的日常生活,在全球范围内造成了数百万人死亡。这种感染的早期和晚期并发症正越来越频繁地被揭示出来;然而,基于信使核糖核酸(mRNA)和基于病毒载体的COVID-19疫苗的推出,为阻止该疾病的传播,尤其是其致死性起到了重要作用。此外,越来越多的疫苗接种不良反应已报告给特定的药物警戒委员会,其中大多数是完全不严重的事件,在接种疫苗后一至三天内即可解决。在本报告中,我们介绍了一名85岁男性患者接种SARS-CoV-2疫苗后继发埃文斯综合征(ES)的病例。据我们所知,这是文献中报道的首例由COVID-19疫苗引起的ES病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3376/9354064/549afe914ff2/cureus-0014-00000026602-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3376/9354064/9555c630f234/cureus-0014-00000026602-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3376/9354064/5d0884acbbaa/cureus-0014-00000026602-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3376/9354064/549afe914ff2/cureus-0014-00000026602-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3376/9354064/9555c630f234/cureus-0014-00000026602-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3376/9354064/5d0884acbbaa/cureus-0014-00000026602-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3376/9354064/549afe914ff2/cureus-0014-00000026602-i03.jpg

相似文献

1
Evans Syndrome Presenting as an Atypical Complication of SARS-CoV-2 Vaccination.埃文斯综合征表现为新型冠状病毒疫苗接种的非典型并发症。
Cureus. 2022 Jul 6;14(7):e26602. doi: 10.7759/cureus.26602. eCollection 2022 Jul.
2
COVID-19 and Immune-Mediated RBC Destruction.新型冠状病毒肺炎与免疫介导的红细胞破坏。
Am J Clin Pathol. 2022 Jun 7;157(6):844-851. doi: 10.1093/ajcp/aqab210.
3
A randomized, double-blind, placebo-controlled phase III clinical trial to evaluate the efficacy and safety of SARS-CoV-2 vaccine (inactivated, Vero cell): a structured summary of a study protocol for a randomised controlled trial.一项评估 SARS-CoV-2 疫苗(灭活,Vero 细胞)有效性和安全性的随机、双盲、安慰剂对照 III 期临床试验:一项随机对照试验研究方案的结构化总结。
Trials. 2021 Apr 13;22(1):276. doi: 10.1186/s13063-021-05180-1.
4
The British variant of the new coronavirus-19 (Sars-Cov-2) should not create a vaccine problem.新冠病毒-19(Sars-Cov-2)的英国变体不应造成疫苗问题。
J Biol Regul Homeost Agents. 2021 Jan-Feb;35(1):1-4. doi: 10.23812/21-3-E.
5
Safety and immunogenicity of the SARS-CoV-2 ARCoV mRNA vaccine in Chinese adults: a randomised, double-blind, placebo-controlled, phase 1 trial.新型冠状病毒 ARCoV mRNA 疫苗在中国成年人中的安全性和免疫原性:一项随机、双盲、安慰剂对照、1 期临床试验。
Lancet Microbe. 2022 Mar;3(3):e193-e202. doi: 10.1016/S2666-5247(21)00280-9. Epub 2022 Jan 24.
6
Insights into COVID-19 Vaccine Development Based on Immunogenic Structural Proteins of SARS-CoV-2, Host Immune Responses, and Herd Immunity.基于 SARS-CoV-2 的免疫原性结构蛋白、宿主免疫反应和群体免疫的 COVID-19 疫苗开发的新见解。
Cells. 2021 Oct 29;10(11):2949. doi: 10.3390/cells10112949.
7
Case Report: Acquired Haemophilia A Following mRNA-1273 Booster Vaccination Against SARS-CoV-2 With Concurrent Diagnosis of Pleomorphic Dermal Sarcoma.病例报告:接种针对SARS-CoV-2的mRNA-1273加强疫苗后获得性甲型血友病并同时诊断为多形性皮肤肉瘤
Front Immunol. 2022 Apr 11;13:868133. doi: 10.3389/fimmu.2022.868133. eCollection 2022.
8
Postvaccination infections among staff of a tertiary care hospital after vaccination with severe acute respiratory syndrome coronavirus 2 vector and mRNA-based vaccines.接种严重急性呼吸综合征冠状病毒 2 载体疫苗和基于 mRNA 的疫苗后,一家三级保健医院工作人员的疫苗接种后感染。
Clin Microbiol Infect. 2022 Apr;28(4):596-601. doi: 10.1016/j.cmi.2021.11.023. Epub 2021 Dec 13.
9
Graves Disease Following the SARS-CoV-2 Vaccine: Case Series.接种新冠病毒疫苗后发生 Graves 病:病例系列。
J Investig Med High Impact Case Rep. 2021 Jan-Dec;9:23247096211063356. doi: 10.1177/23247096211063356.
10
Miller Fisher syndrome following BNT162b2 mRNA coronavirus 2019 vaccination.接种 BNT162b2 mRNA 冠状病毒 2019 疫苗后出现米勒费希尔综合征。
BMC Neurol. 2021 Nov 18;21(1):452. doi: 10.1186/s12883-021-02489-x.

引用本文的文献

1
Evans Syndrome and COVID-19 Infection or Vaccination: A Systematic Review of Case Reports.伊文斯综合征与新冠病毒感染或疫苗接种:病例报告的系统评价
J Hematol. 2025 Jun;14(3):109-123. doi: 10.14740/jh2058. Epub 2025 May 13.
2
Combination of Evans syndrome and COVID-19: a systematic review of reported cases.伊文氏综合征与新型冠状病毒肺炎的合并症:已报告病例的系统评价
Blood Transfus. 2025 Jul-Aug;23(4):365-378. doi: 10.2450/BloodTransfus.860. Epub 2025 Feb 6.
3
Evans' syndrome following vaccination with ChAdOx1 nCoV-19 in a patient with new-onset localized scleroderma.

本文引用的文献

1
New-onset Evans syndrome associated with systemic lupus erythematosus after BNT162b2 mRNA COVID-19 vaccination.接种 BNT162b2 mRNA COVID-19 疫苗后出现与系统性红斑狼疮相关的新发性 Evans 综合征。
Int J Hematol. 2022 Mar;115(3):424-427. doi: 10.1007/s12185-021-03243-2. Epub 2021 Oct 23.
2
Thrombotic Thrombocytopenia after Ad26.COV2.S Vaccination.Ad26.COV2.S疫苗接种后血栓性血小板减少症
N Engl J Med. 2021 May 20;384(20):1964-1965. doi: 10.1056/NEJMc2105869. Epub 2021 Apr 14.
3
Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination.
1例新发局限性硬皮病患者接种ChAdOx1 nCoV-19疫苗后发生伊文斯综合征。
Dermatol Reports. 2022 Nov 21;14(4):9470. doi: 10.4081/dr.2022.9470.
接种 ChAdOx1 nCov-19 疫苗后发生血栓性血小板减少症。
N Engl J Med. 2021 Jun 3;384(22):2092-2101. doi: 10.1056/NEJMoa2104840. Epub 2021 Apr 9.
4
A case of Evans syndrome secondary to COVID-19.一例继发于新型冠状病毒肺炎的伊文氏综合征病例。
Blood Transfus. 2021 Jan;19(1):85-88. doi: 10.2450/2020.0221-20. Epub 2020 Dec 1.
5
Evans' Syndrome: From Diagnosis to Treatment.伊文氏综合征:从诊断到治疗
J Clin Med. 2020 Nov 27;9(12):3851. doi: 10.3390/jcm9123851.
6
Immune Thrombocytopenia Secondary to COVID-19: a Systematic Review.新型冠状病毒肺炎继发免疫性血小板减少症:一项系统评价
SN Compr Clin Med. 2020;2(11):2048-2058. doi: 10.1007/s42399-020-00521-8. Epub 2020 Sep 19.
7
COVID-19 Associated Hemophagocytic Lymphohistiocytosis and Coagulopathy: Targeting the Duumvirate.COVID-19 相关噬血细胞性淋巴组织细胞增生症和凝血障碍:针对双联体。
Indian Pediatr. 2020 Sep 15;57(9):827-833. doi: 10.1007/s13312-020-1962-z. Epub 2020 Jun 24.
8
Mechanisms involved in the development of thrombocytopenia in patients with COVID-19.与 COVID-19 患者血小板减少症发展相关的机制。
Thromb Res. 2020 Sep;193:110-115. doi: 10.1016/j.thromres.2020.06.008. Epub 2020 Jun 5.
9
Evans syndrome in a patient with COVID-19.一名新冠肺炎患者的伊文斯综合征
Br J Haematol. 2020 Jul;190(2):e59-e61. doi: 10.1111/bjh.16846. Epub 2020 Jun 18.
10
Diagnosis and treatment of autoimmune hemolytic anemia in adults: Recommendations from the First International Consensus Meeting.成人自身免疫性溶血性贫血的诊断和治疗:首次国际共识会议的建议。
Blood Rev. 2020 May;41:100648. doi: 10.1016/j.blre.2019.100648. Epub 2019 Dec 5.