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新型冠状病毒肺炎相关的毛霉菌病累及上颌骨。

COVID-19-associated mucormycosis involving the maxilla.

作者信息

Hasheminasab Mahboube, Karizmeh Mojtaba Salehi, Sharifi Reza, Beshkar Majid, Matloubi Narges, Asadi Amir Ali, Nazar Elham

机构信息

Department of Oral and Maxillofacial Surgery and Craniomaxillofacial Research Center, Faculty of Dentistry Tehran University of Medical Sciences Tehran Iran.

Department of Pathology Sina Hospital, Tehran University of Medical Sciences Tehran Iran.

出版信息

Clin Case Rep. 2022 Aug 3;10(8):e6165. doi: 10.1002/ccr3.6165. eCollection 2022 Aug.

Abstract

It is important to increase the awareness and knowledge of head and neck surgeons about the recent surge of craniofacial mucormycosis in COVID-19 patients because early diagnosis and appropriate treatment are essential to improve the outcomes. Here, we describe clinical features, treatment protocols, and outcomes of treatment in eight patients with COVID-19-associated mucormycosis in the maxilla. Consistent with the findings of previous studies, our experience in the management of these eight patients shows that early administration of amphotericin B and prompt aggressive surgery are essential for optimal control of the disease.

摘要

提高头颈外科医生对COVID-19患者中颅面部毛霉菌病近期激增情况的认识和了解非常重要,因为早期诊断和适当治疗对于改善治疗结果至关重要。在此,我们描述了8例上颌骨COVID-19相关性毛霉菌病患者的临床特征、治疗方案及治疗结果。与先前研究结果一致,我们对这8例患者的治疗经验表明,早期给予两性霉素B和及时积极的手术对于最佳控制该病至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7fc/9347695/0c36c72fe806/CCR3-10-e6165-g004.jpg

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