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足部黑霉病:COVID-19 相关毛霉病的一种罕见表现。

Black Fungus of the Foot: An Unusual Presentation of COVID-19-Associated Mucormycosis.

机构信息

*Department of Orthopedic Surgery, Division of Podiatry, NYU Grossman Long Island School of Medicine, Mineola, NY.

†The Ronald O. Perelman Department of Dermatology, NYU Grossman School of Medicine, New York, NY.

出版信息

J Am Podiatr Med Assoc. 2024 Jan-Feb;114(1). doi: 10.7547/22-118.

Abstract

Mucormycosis, also known as black fungus, is a rare but aggressive fungal disease with high morbidity and mortality rates that tends to affect patients who are severely immunocompromised. Early recognition of the infection and prompt intervention is critical for treatment success. In recent years the coronavirus disease of 2019 (COVID-19) pandemic has resulted in a surge in the number of cases of mucormycosis. This study aims to report an unfortunate event involving an immunocompromised elderly man with mucormycosis of the foot who died as a result of sepsis caused by COVID-19. It is important to have a high clinical suspicion for mucormycosis when a clinical lesion develops, and to appropriately perform biopsy the lesion in question, particularly in the context of COVID-19. Raising awareness of COVID-19-associated mucormycosis may allow for early detection of the disease, thus enabling the initiation of rapid treatment, ultimately saving lives.

摘要

毛霉菌病,也被称为黑霉病,是一种罕见但侵袭性强的真菌感染病,发病率和死亡率均较高,往往影响严重免疫功能低下的患者。早期识别感染并及时干预对于治疗成功至关重要。近年来,2019 年冠状病毒病(COVID-19)大流行导致毛霉菌病的病例数量激增。本研究旨在报告一例不幸的足部毛霉菌病免疫功能低下老年患者的病例,该患者因 COVID-19 引起的败血症而死亡。当出现临床病变时,应高度怀疑毛霉菌病,并适当对病变进行活检,尤其是在 COVID-19 背景下。提高对 COVID-19 相关毛霉菌病的认识,可以早期发现该疾病,从而能够迅速开始治疗,最终挽救生命。

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