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癌症在新冠病毒感染患者中是严重的合并症吗?——印度东部一家三级护理中心的回顾性分析

Is cancer significant comorbid condition in COVID 19 infected patients? -A retrospective analysis experienced in a tertiary care center in Eastern India.

作者信息

Mukherjee Kalyan K, Dam Aniruddha, Chakrabarti Deepa, Jatu Debasish, Sengupta Saubhik, Dutta Rita, Majumdar Suparna, Mandal Shyam Sundar, Basu Biswarup, Bhattacharjee Pratiti, Mukherjee Dattatreya, Sengupta Sankar, Chakrabarti Jayanta

机构信息

Department of Medical Oncology and Clinical and Translational Research, Chittaranjan National Cancer Institute, India.

Department of ENT and Covid strategy committee, Chittaranjan National Cancer Institute, India.

出版信息

Ann Med Surg (Lond). 2022 Sep;81:104248. doi: 10.1016/j.amsu.2022.104248. Epub 2022 Aug 3.

DOI:10.1016/j.amsu.2022.104248
PMID:35937633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9347138/
Abstract

BACKGROUND

It was formerly thought that patients with a history of active cancer were more likely to acquire COVID-19; however, new research contradicts this belief due to the impact of economic stress, malnutrition, fear of hospitalization, or therapeutic discontinuation. A cohort-based study was undertaken in Indian regional cancer centre to understand cancer-covid link in patients.

METHOD

A total of 1565 asymptomatic patients were admitted based on thermal screening and evaluation from the screening form from June 2020 to November 2020. The RT-PCR technology was used to assess the COVID 19, and patients who tested positive for COVID 19 were transported to a hospital designated by the government for COVID 19 patients. Patients who tested negative for the COVID 19 virus were transferred to the normal cancer unit to complete their treatment. Patients who tested positive for COVID 19 were referred to the COVID hospital, where their findings were analyzed and correlated with patient age, gender, and cancer stage.

FINDINGS

Out of 1565 patients, 54 patients (3.4%) tested positive. Most of the patients are in 45-59 years age group. As female patients admitted were more in number than males, so predominance of disease is higher in female. 3 patients were symptomatic after admission and 2 were severe and were admitted to the ICU with ventilations. 8 patients died in Cancer and one patient died in COVID 19.

INTERPRETATION

As only 3.4% patients tested positive and only one patient out of 54 had died, so cancer is found not to be a comorbid condition towards COVID 19 patients in the Indian population studied.Funding: This project is not funded.

摘要

背景

以前认为有活动性癌症病史的患者更易感染新冠病毒;然而,由于经济压力、营养不良、对住院的恐惧或治疗中断的影响,新的研究与这一观点相矛盾。在印度地区癌症中心进行了一项基于队列的研究,以了解患者中癌症与新冠病毒的关联。

方法

2020年6月至2020年11月,共有1565名无症状患者根据体温筛查和筛查表评估入院。采用逆转录聚合酶链反应(RT-PCR)技术检测新冠病毒,新冠病毒检测呈阳性的患者被转运至政府指定的新冠患者医院。新冠病毒检测呈阴性的患者被转至正常癌症科室完成治疗。新冠病毒检测呈阳性的患者被转诊至新冠医院,在那里对他们的检查结果进行分析,并与患者年龄、性别和癌症分期相关联。

结果

1565名患者中,54名(3.4%)检测呈阳性。大多数患者年龄在45至59岁之间。由于入院的女性患者数量多于男性,因此女性中疾病的患病率更高。3名患者入院后出现症状,2名病情严重,需使用呼吸机并入住重症监护病房。8名患者死于癌症,1名患者死于新冠病毒感染。

解读

在所研究的印度人群中,由于只有3.4%的患者检测呈阳性,且54名患者中只有1名死亡,因此发现癌症并非新冠患者的合并症。资金:本项目无资金支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/919d/9486438/e4456b91e39d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/919d/9486438/de1863742138/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/919d/9486438/e4456b91e39d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/919d/9486438/de1863742138/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/919d/9486438/e4456b91e39d/gr2.jpg

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