巩膜炎的临床特征、治疗及视力预后：一位眼科医生的经验
Clinical profile, treatment, and visual outcome of scleritis: A single ophthalmologist experience.
作者信息
Magesan Kowsigan, Patnaik Gazal, Majumder Parthopratim Dutta, Biswas Jyotirmay
机构信息
Department of Uvea, Sankara Nethralaya Medical and Vision Research Foundations, Chennai, Tamil Nadu, India.
出版信息
Oman J Ophthalmol. 2022 Jun 29;15(2):153-158. doi: 10.4103/ojo.ojo_168_21. eCollection 2022 May-Aug.
PURPOSE
The purpose of this study was to analyze the clinical profile of patients with scleritis managed by a single ophthalmologist in a tertiary eye care center.
METHODS
This was a retrospective analysis of 107 eyes of 96 patients with scleritis from January 2007 to December 2018.
RESULTS
Female predominance (68%) with a relatively young-onset (46 ± 14 years) of scleritis was observed. Diffuse anterior scleritis (41%) was the most common subtype of scleritis, and the most common systemic association was rheumatoid arthritis (18%). Three-fourth of patients received immunosuppressive treatment (74%) along with corticosteroids. The mean follow-up period was 3 ± 2.5 (range: 0.6-10) years. Necrotizing scleritis was at a 3.5 times higher risk of developing ocular complications. Eighty percent of patients maintained the same vision. Recurrence of scleritis was noted in 25 eyes (23%).
CONCLUSION
Diffuse scleritis is the most common scleritis in our population. Tuberculosis was commonly seen with diffuse scleritis. The likelihood of developing ocular complications (cataract and glaucoma) was higher in necrotizing scleritis, thus requiring periodic monitorization.
目的
本研究旨在分析在一家三级眼科护理中心由一名眼科医生管理的巩膜炎患者的临床特征。
方法
这是一项对2007年1月至2018年12月期间96例巩膜炎患者的107只眼睛进行的回顾性分析。
结果
观察到女性占优势（68%），巩膜炎发病年龄相对较轻（46±14岁）。弥漫性前巩膜炎（41%）是巩膜炎最常见的亚型，最常见的全身关联疾病是类风湿性关节炎（18%）。四分之三的患者在接受皮质类固醇治疗的同时还接受了免疫抑制治疗（74%）。平均随访期为3±2.5（范围：0.6 - 10）年。坏死性巩膜炎发生眼部并发症的风险高3.5倍。80%的患者视力保持不变。25只眼睛（23%）出现巩膜炎复发。
结论
弥漫性巩膜炎是我们研究人群中最常见的巩膜炎类型。弥漫性巩膜炎常伴有结核病。坏死性巩膜炎发生眼部并发症（白内障和青光眼）的可能性更高，因此需要定期监测。
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