Majumder Parthopratim Dutta, Moreker Mayur R, Khadilkar Satish V, Bhosale Bharat, Khetan Vikas
Department of Uvea, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Department of Ophthalmology, Bombay Hospital Institute of Medical Sciences, Mumbai, Maharashtra, India.
Oman J Ophthalmol. 2022 Jun 29;15(2):212-214. doi: 10.4103/ojo.ojo_198_2020. eCollection 2022 May-Aug.
To report a case of non-Hodgkin lymphoma (NHL) that was diagnosed 35-month of initial ocular manifestation. Retrospective chart review. A 53-year-old male presented with painless diminution of vision in both eyes. He subsequently underwent extensive laboratory investigations including multiple vitreous biopsies with a suspicion of intraocular lymphoma. Cytology from the vitreous aspirate failed to diagnose any relevant pathology. After 35-month from the onset of his ocular symptom, a brain biopsy revealed a round cell tumor suggestive of NHL. Even with high index of suspicion, consultation with ocular oncologist, imaging, and diagnostic vitrectomy, the diagnosis of lymphoma remains challenging.
报告一例非霍奇金淋巴瘤（NHL），其在初次眼部表现出现35个月后才得以确诊。回顾性病历审查。一名53岁男性因双眼无痛性视力减退就诊。随后他接受了广泛的实验室检查，包括多次玻璃体活检，怀疑患有眼内淋巴瘤。玻璃体抽吸物的细胞学检查未能诊断出任何相关病变。在出现眼部症状35个月后，脑部活检显示为圆形细胞瘤，提示为NHL。即使高度怀疑，咨询眼科肿瘤学家、进行影像学检查和诊断性玻璃体切割术，淋巴瘤的诊断仍然具有挑战性。
