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眼内淋巴瘤的视网膜下抽吸活检

Subretinal aspiration biopsy of ocular lymphoma.

作者信息

Ciulla T A, Pesavento R D, Yoo S

机构信息

Department of Ophthalmology, Indiana University School of Medicine, USA.

出版信息

Am J Ophthalmol. 1997 Mar;123(3):420-2. doi: 10.1016/s0002-9394(14)70150-3.

DOI:10.1016/s0002-9394(14)70150-3
PMID:9063264
Abstract

PURPOSE

Large-cell lymphoma can be difficult to diagnose because vitreous biopsies may fail to disclose neoplastic cells.

METHODS

We report one such case in which diagnosis was confirmed by subretinal aspiration of yellow-white infiltrates using a pars plana approach.

RESULTS

A 67-year-old woman with recurrent bilateral uveitis was diagnosed with large-cell lymphoma by subretinal aspiration of yellow-white infiltrates after two vitreous biopsies and a concurrent retinal biopsy failed to confirm the diagnosis.

CONCLUSIONS

When the suspicion of intraocular lymphoma remains high despite previous negative vitreous biopsies, retinal biopsy and aspiration biopsy of subretinal lesions may enhance the diagnostic yield.

摘要

目的

大细胞淋巴瘤可能难以诊断,因为玻璃体活检可能无法发现肿瘤细胞。

方法

我们报告了这样一例病例,通过经扁平部入路对黄白色浸润灶进行视网膜下穿刺抽吸,确诊了该病。

结果

一名67岁复发性双侧葡萄膜炎女性患者,在两次玻璃体活检及一次同期视网膜活检均未能确诊后,经对黄白色浸润灶进行视网膜下穿刺抽吸,被诊断为大细胞淋巴瘤。

结论

尽管先前玻璃体活检结果为阴性,但如果眼内淋巴瘤的怀疑仍很高,视网膜活检及视网膜下病变的穿刺活检可能会提高诊断率。

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Subretinal aspiration biopsy of ocular lymphoma.眼内淋巴瘤的视网膜下抽吸活检
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Primary intraocular lymphoma of T-cell type: report of a case and review of the literature.T 细胞型原发性眼内淋巴瘤:1例报告并文献复习
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[Diagnostic vitrectomy in uveitis: possibilities of molecular biology].[葡萄膜炎中的诊断性玻璃体切除术:分子生物学的可能性]
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Graefes Arch Clin Exp Ophthalmol. 2003 Oct;241(10):860-70. doi: 10.1007/s00417-003-0749-y. Epub 2003 Sep 30.