酒石酸布托啡诺与盐酸哌替啶在平衡麻醉中的双盲比较
Double-blind comparison of butorphanol tartrate and meperidine hydrochloride in balanced anaesthesia.
作者信息
Stehling L C, Zauder H L
出版信息
J Int Med Res. 1978;6(5):384-7. doi: 10.1177/030006057800600506.
PMID:359382
Abstract
Butorphanol tartrate, a synthetic morphinan which has analgesic agonist and antagonist properties, was compared with meperidine for balanced anaesthesia. The two agents were found to be comparable in efficacy, maintenance of cardiovascular stability, and incidence of side-effects. Butorphanol has the advantage of being non-narcotic and having a lower propensity for addiction. Because of its antagonist properties, there appears to be a limit to its depressant effects on respiration.
摘要
酒石酸布托啡诺是一种具有镇痛激动剂和拮抗剂特性的合成吗啡喃，将其与哌替啶用于平衡麻醉进行比较。发现这两种药物在疗效、维持心血管稳定性和副作用发生率方面具有可比性。布托啡诺具有非麻醉性且成瘾倾向较低的优点。由于其拮抗特性，其对呼吸的抑制作用似乎存在限度。
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