[二巯丙醇和乙酰半胱氨酸对致敏豚鼠脂质过氧化及红细胞抗氧化系统的影响]
[Effect of unithiol and acetylcysteine on lipid peroxidation and the erythrocyte antioxidant system in sensitized guinea pigs].
作者信息
Shleĭkin A G, Zubzhitskiĭ Iu N, Baskovich G A, Kolmakov V N, Rodionova L P
出版信息
Biull Eksp Biol Med. 1987 May;103(5):548-50.
PMID:3593922
Abstract
The effect of unithiol and acetylcysteine on lipid peroxidation, thioldisulfide equilibrium, glucose-6-phosphate dehydrogenase, glutathione reductase and lactate dehydrogenase activity and on erythrocyte resistance was studied in guinea-pigs during sensitization with C. maltosa. Sensibilized animals receiving thiol antioxidants showed partial restoration of normal biochemical levels.
摘要
在豚鼠被麦芽假丝酵母致敏的过程中，研究了二巯丙醇和乙酰半胱氨酸对脂质过氧化、硫醇-二硫化物平衡、葡萄糖-6-磷酸脱氢酶、谷胱甘肽还原酶和乳酸脱氢酶活性以及对红细胞抵抗力的影响。接受硫醇抗氧化剂的致敏动物显示出正常生化水平的部分恢复。
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