Department of Medicine, University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Department of Surgery, University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Front Endocrinol (Lausanne). 2022 Jul 22;13:957369. doi: 10.3389/fendo.2022.957369. eCollection 2022.
The coexistence of insulinoma and type 2 diabetes is rare and the diagnostic process is often challenging. Continuous glucose monitoring system devices, which are more readily available nowadays, provide a useful tool for the diagnosis and evaluation of treatment response. Curative surgery is often the mainstay of treatment for insulinoma. Here, we report a Chinese patient with insulinoma diagnosed simultaneously with type 2 diabetes. His insulinoma was managed with endoscopic ultrasound guided-radiofrequency ablation (EUS-RFA) and the patient achieved complete resolution of hypoglycaemic episodes. The case illustrates that while EUS-RFA is an emerging non-invasive treatment modality for pancreatic lesions, limitations exist especially when histological confirmation is essential.
胰岛素瘤合并 2 型糖尿病较为罕见，诊断过程往往具有挑战性。如今，连续血糖监测系统设备为诊断和评估治疗反应提供了有用的工具。治愈性手术通常是胰岛素瘤治疗的主要方法。本文报告了一位中国胰岛素瘤合并 2 型糖尿病患者，其胰岛素瘤采用内镜超声引导下射频消融（EUS-RFA）治疗，患者低血糖发作完全缓解。该病例说明，虽然 EUS-RFA 是一种新兴的胰腺病变非侵入性治疗方法，但当需要组织学确认时，仍存在局限性。
