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锡霍特-阿林病毒,一种从滨海边疆区全沟硬蜱中分离出的心脏病毒属(微小核糖核酸病毒科)新成员。

Sikhote-Alin virus, a new member of the cardiovirus group (Picornaviridae) isolated from Ixodes persulcatus ticks in Primorie Region.

作者信息

Lvov D K, Leonova G N, Gromashevsky V L, Shestakov V L, Gofman Y P, Skvortsova T M, Klimenko S M, Berezina L K, Zakaryan V A, Safronov A V, Belousova R V

出版信息

Acta Virol. 1978 Nov;22(6):458-63.

PMID:35943
Abstract

A virus, designated Sikhote-Alin, was isolated in 1970 from Ixodes persulcatus ticks collected from a wild boar in the Primorie region (U.S.S.R.) Sikhote-Alin virus showed no haemagglutinating activity and no antigenic relationships with arboviruses of 12 antigenic groups, 17 ungrouped tick-borne arboviruses, porcine enteroviruses and coxsackie A (types 1-18) viruses. An one-way antigenic relationship was demonstrated by complement fixation with cardioviruses (Mengo and Columbia-SK strains). The virus contains RNA, is resistant to lipid solvents, highly thermostable in the presence of 1 M MgCl2 and its size is over 20 nm but less than 25 nm. All these properties make it possible to consider it as a new member of the cardiovirus group (genus Enterovirus; Picornaviridae).

摘要

1970年,从苏联滨海边疆区一头野猪身上采集的全沟硬蜱中分离出一种病毒,命名为锡霍特-阿林病毒。锡霍特-阿林病毒无血凝活性,与12个抗原组的虫媒病毒、17种未分组的蜱传虫媒病毒、猪肠道病毒和柯萨奇A(1 - 18型)病毒均无抗原关系。通过与心病毒(门戈病毒和哥伦比亚-SK株)进行补体结合试验,证明存在单向抗原关系。该病毒含有RNA,对脂溶剂有抗性,在1 M MgCl2存在下具有高度热稳定性,其大小超过20 nm但小于25 nm。所有这些特性使其有可能被视为心病毒属(肠道病毒属;小核糖核酸病毒科)的一个新成员。

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