Servicio de Endoscopia, Hospital General de México Dr. Eduardo Liceaga.
Departamento de Endoscopia, Hospital Ángeles del Pedregal.
Cir Cir. 2022;90(S1):15-24. doi: 10.24875/CIRU.21000771.
To evaluate efficacy and safety between dual angiotherapy (endocoil plus N-butyl-cyanoacrylate) guided by endoscopic ultrasound) versus N-butyl-cyanoacrylate in the secondary prophylaxis of gastroesophageal varices (GOV).
Prospective non-inferiority study comparing two gastric variceal eradication techniques. We evaluated technical and clinical success, GOV occlusion and eradication, rebleeding, reoperation, GOV-free period, complications, and mortality. Chi square for categorical variables and Student's t for numerical variables with a significance level of 0.05.
There were 68 patients (average age 55.5 ± 10 years, women 44 (64.7%) and average body mass index 25.7 ± 3.5 kg/m). The most frequent cause was alcoholic steatohepatitis (58%). Dual therapy had greater technical (100% vs. 94.3%) and clinical (100% vs. 85%) success. Obliteration was faster (100 vs. 79.2%). This group only required one session. The GOV size was 24 ± 14 mm and 1-2 endocoils were placed. The median follow-up was 221 days. The reoperation-free rate was high (100% vs. 94%; p = 0.9).
Dual angiotherapy guided by endoscopic ultrasound and cyanoacrylate injection are effective for the eradication of GOV without differences in adverse event rates.
评估内镜超声引导下双血管治疗（线圈加 n-丁基-氰基丙烯酸酯）与 n-丁基-氰基丙烯酸酯在胃食管静脉曲张（GOV）二级预防中的疗效和安全性。
前瞻性非劣效性研究比较了两种胃静脉曲张消除技术。我们评估了技术和临床成功率、GOV 闭塞和消除、再出血、再手术、GOV 无复发期、并发症和死亡率。分类变量用卡方检验，数值变量用学生 t 检验，显著性水平为 0.05。
共纳入 68 例患者（平均年龄 55.5 ± 10 岁，女性 44 例（64.7%），平均体重指数 25.7 ± 3.5 kg/m²）。最常见的病因是酒精性脂肪性肝炎（58%）。双治疗组具有更高的技术成功率（100%比 94.3%）和临床成功率（100%比 85%）。闭塞更快（100%比 79.2%）。该组仅需一次治疗。GOV 大小为 24 ± 14 mm，放置 1-2 个线圈。中位随访时间为 221 天。无再手术率较高（100%比 94%；p = 0.9）。
内镜超声引导下双血管治疗联合氰基丙烯酸酯注射治疗 GOV 有效，不良事件发生率无差异。
