8号染色体四体：急性非淋巴细胞白血病中一种有趣且罕见的细胞遗传学现象。
Tetrasomy of chromosome 8: an interesting and rare cytogenetic phenomenon in acute nonlymphocytic leukemia.
作者信息
Jani Sait S N, Raza A, Sandberg A A
出版信息
Cancer Genet Cytogenet. 1987 Aug;27(2):269-71. doi: 10.1016/0165-4608(87)90009-4.
PMID:3594416
Abstract
Trisomy of chromosome #8 is a change commonly associated with acute nonlymphocytic leukemia (ANLL). However, tetrasomy of chromosome #8 in ANLL as a single chromosome change without accompanying abnormalities is extremely rare and, to the best of our knowledge, has not been reported to date. We present here a case of acute monocytic leukemia (AMoL, FAB M5b) with four copies of chromosome #8.
摘要
8号染色体三体是一种常与急性非淋巴细胞白血病（ANLL）相关的染色体改变。然而，在急性非淋巴细胞白血病中，8号染色体四体作为单一的染色体改变且无伴随异常的情况极为罕见，据我们所知，迄今为止尚未见报道。我们在此报告一例具有4条8号染色体的急性单核细胞白血病（AMoL，FAB M5b）病例。
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