新冠病毒感染后接种科兴新冠疫苗的个体中，CD8⁺CD45RA⁺CCR7⁺CD62L⁺ T细胞减少。
Decrease in CD8CD45CCR7CD62L T cells in individuals vaccinated with Sinovac-CoronaVac following COVID-19 infection.
作者信息
Fonseca Dâmaris C S C, Rocha Mirtes C B, Pereira Lucca A, Botega Leticia P, Cutrim Susanne C P F, Silva Fabiano V, Batista Flávio D, Rêgo Adriana S, Falcai Ângela, Lima-Neto Lídio G, Santos Ana Paula S A, Carvalho Rafael C, Sousa Eduardo M
机构信息
Graduate Program in Microbial Biology, CEUMA University - UniCEUMA, São Luís, Brazil.
Central Public Health Laboratory of Maranhão - LACEN-MA, São Luís, Brazil; Graduate Program in Health Sciences, Federal University of Maranhão - UFMA, São Luís, Brazil.
出版信息
Clin Immunol. 2022 Sep;242:109092. doi: 10.1016/j.clim.2022.109092. Epub 2022 Aug 6.
Vaccines induce antibodies, but T cell responses are also important for protection against Coronavirus disease 2019. Here, we analyzed the frequency of memory T cells in infected and/or vaccinated individuals and observed a decrease in central memory T cells in individuals who were vaccinated following COVID-19 infection.
疫苗可诱导产生抗体，但T细胞反应对于预防2019冠状病毒病也很重要。在此，我们分析了感染和/或接种疫苗个体中记忆T细胞的频率，并观察到在COVID-19感染后接种疫苗的个体中，中央记忆T细胞有所减少。
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