Department of General Surgery, Kingsway Hospitals, Nagpur, India.
Department of Surgical Oncology, Kingsway Hospitals, Nagpur, India.
BMJ Case Rep. 2022 Aug 9;15(8):e250758. doi: 10.1136/bcr-2022-250758.
Kimura's disease is a rare, benign entity that causes subcutaneous angioblastic lymphoid hyperplasia with eosinophilia. It usually presents with subcutaneous lymphoid swellings with regional lymphadenopathy and salivary gland masses. Kimura's disease is frequently associated with renal involvement, which includes proteinuria and nephrotic syndrome as the most common presentations. This report presents a case of a man in his early 20s with a swelling in the medial aspect of the distal left arm with two previous episodes of nephrotic syndrome. Multiple enlarged axillary lymph nodes and epitrochlear nodes were noted. Ultrasonography revealed a mixed echogenic mass with enlarged lymph nodes. MRI showed a heterogeneous hyperintense lesion. Image-guided fine-needle aspiration showed multiple lymphocytes and eosinophils suggestive of Kimura's disease. The swelling was surgically excised under general anaesthesia. Histopathology of the excised mass confirmed the diagnosis of Kimura's disease.
木村病是一种罕见的良性病变，可导致伴有嗜酸性粒细胞增多的皮下血管淋巴样增生。它通常表现为伴有区域性淋巴结病和唾液腺肿大的皮下淋巴样肿胀。木村病常与肾脏受累有关，包括蛋白尿和肾病综合征是最常见的表现。本报告介绍了一例 20 多岁的男性，其左前臂远端内侧有一处肿胀，曾有两次肾病综合征发作。多个腋窝和肘前淋巴结肿大。超声检查显示混合回声肿块伴淋巴结肿大。MRI 显示不均匀高信号病变。影像引导下细针抽吸显示多个淋巴细胞和嗜酸性粒细胞，提示为木村病。肿胀在全身麻醉下进行了手术切除。切除肿块的组织病理学检查证实了木村病的诊断。
