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木村病:腮腺肿大的罕见病因。

Kimura's Disease: A Rare Cause of Parotid Swelling.

作者信息

Muniraju M, Dechamma Shruthi

机构信息

1Department of ENT and Head and Neck Surgery, Dr. B.R. Ambedkar Medical College, Bangalore, India.

Bangalore, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):589-593. doi: 10.1007/s12070-018-1421-5. Epub 2018 Jun 18.

Abstract

Kimura's disease also known as subcutaneous angioblastic lymphoid hyperplasia with peripheral eosinophilia is a rare clinicopathological entity. It is a chronic granulomatous disease of unknown etiology. The clinical presentation varies from subcutaneous swellings of the head and neck region with regional lymphadenopathy with salivary gland involvement to systemic manifestations like nephrotic syndrome. The clinical features are mild, rarely life threatening. The present article is a case report of Kimura's disease presenting as multiple swellings at the left temporal region, left parotid and bilateral post auricular region. Though the lesion is benign, the cosmetic disfigurement caused by the swellings was of significant concern to our patient. MRI Scan was suggestive of a parotid swelling extending into the temporal and post auricular region of the left side. Surgical modality of treatment was adopted- Superficial Parotidectomy with excision of subcutaneous swellings. Histopathological examination confirmed the diagnosis of Kimura's disease. The mode of presentation as multiple large swellings with the involvement of the parotid gland created a diagnostic dilemma, hence this article intends to consider Kimura's disease as a rare but possible cause of a parotid swelling.

摘要

木村病又称伴有外周嗜酸性粒细胞增多的皮下血管母细胞性淋巴组织增生症,是一种罕见的临床病理实体。它是一种病因不明的慢性肉芽肿性疾病。临床表现多样,从伴有区域淋巴结病及唾液腺受累的头颈部皮下肿胀到肾病综合征等全身表现。临床特征较轻,很少危及生命。本文是一例木村病的病例报告,表现为左侧颞区、左侧腮腺及双侧耳后区域的多处肿胀。尽管病变是良性的,但肿胀导致的容貌毁损引起了患者的极大关注。磁共振成像扫描提示腮腺肿胀延伸至左侧颞区和耳后区域。采用手术治疗方式——腮腺浅叶切除术并切除皮下肿胀。组织病理学检查确诊为木村病。以多处大肿胀伴腮腺受累的表现方式造成了诊断上的困境,因此本文旨在将木村病视为腮腺肿胀的一种罕见但可能的病因。

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