Department of Respiratory Medicine, National Hospital Organization Himeji Medical Center, Himeji-shi, Hyogo, Japan.
Medicine (Baltimore). 2022 Aug 5;101(31):e29377. doi: 10.1097/MD.0000000000029377.
The effectiveness of thoracoscopic biopsy as a diagnostic method for pleural diseases has been reported; however, obtaining a sufficient specimen size is sometimes difficult. Therefore, an ancillary technique, the precut technique using an injection needle, was devised to address this problem. This study aimed to evaluate the effectiveness and safety of the novel precut technique in patients with undiagnosed pleural effusion. This retrospective study included 22 patients who underwent pleural biopsy using the precut technique to examine exudative pleural effusion of unknown etiology. Thoracoscopy was performed under local anesthesia. The biopsy procedure was performed as follows: a needle was inserted into the pleura around the lesion using a semiflexible thoracoscope; the needle was positioned to make an incision in the pleura while injecting 1% lidocaine with epinephrine and lifting the pleura from the fascia; 2 or 3 precut incision lines were arranged in a triangle; and the specimen was obtained from the parietal pleura using forceps or a cryoprobe. Patient data including age, number of biopsies, biopsy specimen size, pathological and final diagnosis, and postoperative complications were examined. All patients were male with an average age of 74 years. Pleural effusion was found on the right and left sides in 16 and 6 patients, respectively. The average major axis of the biopsy specimens was 18 mm (range, 10-30 mm), which was sufficient to establish a pathological diagnosis. Only 1 patient experienced minor temporal bleeding as a complication. The precut technique enabled the procurement of specimens sufficient in size for pleural biopsy.
胸腔镜活检作为一种诊断胸膜疾病的方法已经得到了证实;然而,有时获取足够的标本大小是很困难的。因此,设计了一种辅助技术,即使用注射针的预切开技术,以解决这个问题。本研究旨在评估新型预切开技术在不明原因胸腔积液患者中的有效性和安全性。本回顾性研究纳入了 22 名接受预切开技术进行胸腔活检的患者,以检查渗出性胸腔积液的病因不明。胸腔镜检查在局部麻醉下进行。活检程序如下:使用半刚性胸腔镜将针插入病变周围的胸膜;将针插入胸膜,同时注射 1%利多卡因加肾上腺素,并将胸膜从筋膜提起;在三角形中安排 2 或 3 个预切开切口线;使用钳子或冷冻探针从壁层胸膜获取标本。检查了包括年龄、活检次数、活检标本大小、病理和最终诊断以及术后并发症在内的患者数据。所有患者均为男性,平均年龄为 74 岁。16 名患者的胸腔积液位于右侧,6 名患者的胸腔积液位于左侧。活检标本的平均长轴为 18 毫米(范围为 10-30 毫米),足以进行病理诊断。仅 1 名患者出现轻微的暂时出血并发症。预切开技术能够获取足够大小的胸膜活检标本。