Department of Psychiatry, Kyungpook National University Hospital, Daegu, South Korea.
Department of Psychiatry, School of Medicine, Kyungpook National University, Daegu, South Korea.
Medicine (Baltimore). 2022 Aug 5;101(31):e29581. doi: 10.1097/MD.0000000000029581.
With the aging of the population, the number of people with age-related memory complaints has also increased. The purpose of this study was to develop a cognitive rehabilitation program based on mnemonic skills and memory compensatory strategies (CRM) and to investigate the effects of CRM in community-dwelling older adults without dementia.
This study was an open-label, single-arm, pilot study. We developed a CRM program comprising 8 weekly sessions. The study participants consisted of older adults with normal cognitive function and mild cognitive impairment (MCI). They were recruited from eight dementia counseling centers and one senior welfare center. To assess the effects of CRM, we administered the following tests at baseline and after completion of the program: Subjective Memory Complaints Questionnaire, the Short form of Geriatric Depression Scale, the Euro Quality of life-5 Dimension, and the Consortium to Establish a Registry for Alzheimer's Disease Neuropsychological Assessment Battery.
Thirty-two participants completed the study. Among older adults with normal cognitive function, CRM showed significant improvement in verbal memory function. Among the older adults with MCI, CRM showed significant improvements in language ability, verbal recognition memory, nonverbal memory, attention, and processing speed.
CRM improved cognitive function in two distinct populations, older adults with normal cognitive function and older adults with MCI. Additionally, our preliminary findings suggest that older adults with MCI show cognitive improvement in both the trained and non-trained cognitive domains.
随着人口老龄化,出现与年龄相关的记忆问题的人数也有所增加。本研究旨在开发一种基于记忆技巧和记忆补偿策略的认知康复计划,并调查该计划对无痴呆症的社区居住老年人的影响。
本研究为开放标签、单臂、试点研究。我们制定了一个包含 8 周课程的 CRM 计划。研究参与者包括认知功能正常和轻度认知障碍(MCI)的老年人。他们是从八个痴呆症咨询中心和一个老年福利院招募的。为了评估 CRM 的效果,我们在基线和完成计划后进行了以下测试:主观记忆抱怨问卷、老年抑郁量表简短版、欧洲生活质量 5 维度量表和阿尔茨海默病神经心理评估电池联合会。
32 名参与者完成了研究。在认知功能正常的老年人中,CRM 显示出言语记忆功能的显著改善。在 MCI 老年人中,CRM 显示出语言能力、言语识别记忆、非言语记忆、注意力和处理速度的显著改善。
CRM 改善了认知功能正常和 MCI 老年人这两个不同人群的认知功能。此外,我们的初步研究结果表明,MCI 老年人在训练和非训练认知领域都表现出认知改善。