Department of Psychology, Université du Québec à Trois-Rivières, Trois-Rivieres, QC, Canada.
Research Center of the Institut Universitaire de Gériatrie de Montréal, Montréal, QC, Canada.
Brain Inj. 2022 Jul 3;36(8):985-990. doi: 10.1080/02699052.2022.2109734. Epub 2022 Aug 9.
This longitudinal study aimed to evaluate olfactory perception in patients with first time mild traumatic brain injury (mTBI) 2-4 weeks (baseline) and 6 months (follow-up) following their trauma.
At baseline, we enrolled 107 participants (54 healthy controls; 53 patients with mTBI). Thirty-nine healthy controls and 32 patients with mTBI returned for follow-up. We assessed odor detection (yes/no paradigm) and odor perception with a self-reported evaluation of intensity and pleasantness of four common odorants, by using an olfactometer, i.e., a computer controlled automated odor presentation device.
At baseline, patients with mTBI showed significantly more difficulty detecting odors; however, they perceived them as more intense and less pleasant. These effects vanished at follow-up.
These results suggest that patients with mTBI suffer from altered olfactory detection and perception in the first weeks following their trauma. This may have an impact on eating behavior and quality of life. Further, our data suggest recovery of olfactory function within the first six months following a head trauma.
本纵向研究旨在评估首次轻度创伤性脑损伤（mTBI）患者在创伤后 2-4 周（基线）和 6 个月（随访）时的嗅觉感知。
在基线时，我们招募了 107 名参与者（54 名健康对照；53 名 mTBI 患者）。39 名健康对照和 32 名 mTBI 患者返回进行随访。我们使用嗅觉计（即计算机控制的自动气味呈现装置）评估气味检测（是/否范式）和嗅觉感知，包括对四种常见气味剂的强度和愉悦感的自我报告评估。
在基线时，mTBI 患者在检测气味方面明显存在更多困难；然而，他们感知到的气味强度更高，愉悦度更低。这些影响在随访时消失。
这些结果表明，mTBI 患者在创伤后最初几周内会出现嗅觉检测和感知的改变。这可能会对饮食行为和生活质量产生影响。此外，我们的数据表明，在头部创伤后六个月内，嗅觉功能会恢复。
