Department of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
Indian J Dent Res. 2022 Jan-Mar;33(1):75-79. doi: 10.4103/ijdr.IJDR_117_20.
Many attempts have been made to enhance the anti-cariogenic properties of the conventional glass ionomer through incorporation of variable materials. However, most importantly, the incorporation of such materials should not jeopardise the physical or mechanical properties of the final restoration.
To investigate the effect of adding silver nanoparticles (Ag-NPs) and titanium dioxide nanoparticles (TiO-NPs) to conventional glass ionomer cement (GIC) on its anti-bacterial effect against Streptococcus mutans (S. mutans), fluoride ion release, and compressive strength (CS).
This study was an in vitro investigation where 30-disc specimens were prepared in each of the three studied groups.
The specimens were categorized into the control group (Group C), in which conventional GIC was used, and Group Ag and Group Ti, in which 5 wt% of Ag-NP and TiO-NP were added, respectively, to GIC powder. In each group, the anti-bacterial effect against S. mutans, fluoride ion release at 24 hours and 14 and 28 days, and CS were assessed. Data were analysed using one-way analysis of variance, followed by Tukey honest significant difference post-hoc test.
Both Ag and Ti groups showed a significantly higher anti-bacterial effect than the control group. Ag-NP increased fluoride ion release, whereas TiO-NP decreased fluoride release; however, cumulative ion release of both experimental groups did not differ significantly compared to the control group. Adding Ag-NP and TiO-NP increased CS, yet only the Ti group showed the highest CS mean value that was statistically significant compared to other groups.
Adding 5 wt% TiO-NP or Ag-NP to conventional GIC significantly increased its anti-bacterial effect and its CS without affecting fluoride release.
为了提高传统玻璃离子体的抗龋性能，人们尝试了许多方法，通过加入各种材料来实现。然而，最重要的是，加入这些材料不应损害最终修复体的物理或机械性能。
研究在传统玻璃离子体水门汀（GIC）中加入纳米银（Ag-NPs）和纳米二氧化钛（TiO-NPs）对其抗变形链球菌（S. mutans）效果、氟离子释放和抗压强度（CS）的影响。
本研究为体外研究，每个研究组制备 30 个样本。
将样本分为对照组（C 组），使用常规 GIC；Ag 组和 Ti 组，分别在 GIC 粉末中添加 5wt%的 Ag-NP 和 TiO-NP。在每组中，评估对 S. mutans 的抗菌效果、24 小时、14 天和 28 天的氟离子释放以及 CS。使用单因素方差分析对数据进行分析，然后进行 Tukey 诚实显著差异事后检验。
Ag 组和 Ti 组的抗菌效果均明显高于对照组。Ag-NP 增加了氟离子的释放，而 TiO-NP 降低了氟离子的释放；然而，与对照组相比，两个实验组的累积离子释放量没有显著差异。添加 Ag-NP 和 TiO-NP 增加了 CS，但只有 Ti 组的 CS 平均值显著高于其他组。
在传统 GIC 中添加 5wt%的 TiO-NP 或 Ag-NP 可显著提高其抗菌效果和 CS，而不影响氟离子释放。
