Qian Maolin, Wang Lan, Xing Jiajun, Shan Xiao, Wu Juan, Liu Xiaoqin
School of Medicine, Nantong University, Nantong, People's Republic of China.
Department of Gynecology, Affiliated Hospital of Nantong University, Nantong, People's Republic of China.
Psychol Health Med. 2023 Feb;28(2):494-508. doi: 10.1080/13548506.2022.2110270. Epub 2022 Aug 10.
Cervical cancer (CC) is a common malignant gynaecological tumour. However, as survival rates have improved, increasing attention has focused on the quality of the survivors' sex lives. We conducted a meta-analysis to investigate the prevalence and severity of female sexual dysfunction (FSD) in women with CC. We searched the PubMed, Cochrane Library, Embase, China National Knowledge Infrastructure, and Wang Fang databases, and extracted data from all studies published up to December 2020 that evaluated sexual dysfunction in patients with CC with the female sexual function index (FSFI). Studies were screened according to specific inclusion and exclusion criteria, and the qualities of the included studies were evaluated. Sixteen studies with a total of 2009 women with CC, including 1306 women with FSD, were included in the meta-analysis. Among patients with CC, the incidence of FSD was 80% (95% confidence interval (95%CI) 0.74-0.87) and the average FSFI score was 20.25 (95%CI 18.96-21.53). These results revealed a high prevalence of FSD and poor sexual function among women with CC, suggesting a need to assess sexual function regularly in these women with CC to improve early recognition of FSD and thereby allow appropriate interventions to enhance the sex life of affected patients.
宫颈癌(CC)是一种常见的妇科恶性肿瘤。然而,随着生存率的提高,人们越来越关注幸存者的性生活质量。我们进行了一项荟萃分析,以调查CC女性中女性性功能障碍(FSD)的患病率和严重程度。我们检索了PubMed、Cochrane图书馆、Embase、中国知网和万方数据库,并从截至2020年12月发表的所有使用女性性功能指数(FSFI)评估CC患者性功能障碍的研究中提取数据。根据特定的纳入和排除标准筛选研究,并评估纳入研究的质量。荟萃分析纳入了16项研究,共2009例CC女性,其中1306例患有FSD。在CC患者中,FSD的发生率为80%(95%置信区间(95%CI)0.74 - 0.87),平均FSFI评分为20.25(95%CI 18.96 - 21.53)。这些结果显示CC女性中FSD的患病率很高且性功能较差,这表明需要对这些CC女性定期进行性功能评估,以提高对FSD的早期识别,从而进行适当干预,改善受影响患者的性生活。