• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

重新评估早发性脊柱侧凸治疗选择的共识和不确定性:10 年更新。

Re-evaluating consensus and uncertainty among treatment options for early onset scoliosis: a 10-year update.

机构信息

Department of Orthopedic Surgery, Boston Children's Hospital, Boston, MA, 02115, USA.

Department of Orthopaedic Surgery, Harvard Medical School, Boston, MA, 02115, USA.

出版信息

Spine Deform. 2023 Jan;11(1):11-25. doi: 10.1007/s43390-022-00561-1. Epub 2022 Aug 10.

DOI:10.1007/s43390-022-00561-1
PMID:35947359
Abstract

PURPOSE

Consensus and uncertainty in early onset scoliosis (EOS) treatment were evaluated in 2010. It is currently unknown how treatment preferences have evolved over the past decade. The purpose of this study was to re-evaluate consensus and uncertainty among treatment options for EOS patients to understand how they compare to 10 years ago.

METHODS

11 pediatric spinal surgeons (similar participants as in 2010) were invited to complete a survey of 315 idiopathic and neuromuscular EOS cases (same cases as in 2010). Treatment options included the following: conservative management, distraction-based methods, growth guidance/modulation, and arthrodesis. Consensus was defined as ≥ 70% agreement, and uncertainty was < 70%. Associations between case characteristics and consensus for treatments were assessed via chi-squared and multiple regression analyses. Case characteristics associated with uncertainty were described.

RESULTS

Eleven surgeons [31.7 ± 7.8 years of experience] in the original 2010 cohort completed the survey. Consensus for conservative management was found in idiopathic patients aged ≤ 3, whereas in 2010, some of these cases were selected for surgery. There is currently consensus for casting idiopathic patients aged 1 or 2 with moderate curves, whereas in 2010, there was uncertainty between casting and bracing. Among neuromuscular cases with consensus for surgery, arthrodesis was chosen for patients aged 9 with larger curves.

CONCLUSION

Presently, preferences for conservative management have increased in comparison to 2010, and casting appears to be preferred over bracing in select infantile cases. Future research efforts with higher levels-of-evidence should be devoted to elucidate the areas of uncertainty to improve care in the EOS population.

LEVEL OF EVIDENCE

Level V.

摘要

目的

2010 年评估了早发性脊柱侧凸(EOS)治疗中的共识和不确定性。目前尚不清楚过去十年中治疗偏好是如何演变的。本研究的目的是重新评估 EOS 患者治疗选择的共识和不确定性,以了解它们与 10 年前相比有何不同。

方法

邀请 11 名儿科脊柱外科医生(与 2010 年相同的参与者)完成了一项针对 315 例特发性和神经肌肉性 EOS 病例(与 2010 年相同的病例)的调查。治疗选择包括以下几种:保守治疗、牵引法、生长引导/调节和融合术。共识定义为≥70%的一致性,不确定性<70%。通过卡方检验和多元回归分析评估病例特征与治疗共识之间的关系。描述与治疗不确定性相关的病例特征。

结果

在最初的 2010 队列中,有 11 名外科医生[31.7±7.8 年的经验]完成了调查。对于年龄≤3 岁的特发性患者,保守治疗的共识得以达成,而在 2010 年,这些病例中的一些选择了手术治疗。目前对于年龄为 1 或 2 岁、中度曲线的特发性患者,使用石膏固定有共识,但在 2010 年,对于石膏固定和支具固定之间存在不确定性。在具有手术共识的神经肌肉性病例中,对于年龄为 9 岁、曲线较大的患者,选择融合术。

结论

与 2010 年相比,目前对保守治疗的偏好有所增加,并且在选择婴儿病例时,石膏固定似乎优于支具固定。未来应投入更高水平证据的研究工作,以阐明不确定性领域,改善 EOS 人群的治疗效果。

证据等级

V 级。

相似文献

1
Re-evaluating consensus and uncertainty among treatment options for early onset scoliosis: a 10-year update.重新评估早发性脊柱侧凸治疗选择的共识和不确定性:10 年更新。
Spine Deform. 2023 Jan;11(1):11-25. doi: 10.1007/s43390-022-00561-1. Epub 2022 Aug 10.
2
Evaluating consensus and uncertainty among treatment options for early-onset scoliosis: new generation and international perspectives.评估早发性脊柱侧凸治疗方案的共识和不确定性:新一代和国际视角。
Spine Deform. 2023 Sep;11(5):1271-1282. doi: 10.1007/s43390-023-00713-x. Epub 2023 Jun 6.
3
More experienced surgeons less likely to fuse: a focus group review of 315 hypothetical EOS cases.经验更丰富的外科医生进行融合手术的可能性更低:对315例虚拟EOS病例的焦点小组评估
J Pediatr Orthop. 2013 Jan;33(1):68-74. doi: 10.1097/BPO.0b013e318279c501.
4
Evaluating the extent of clinical uncertainty among treatment options for patients with early-onset scoliosis.评估早发性脊柱侧凸患者治疗选择的临床不确定性程度。
J Bone Joint Surg Am. 2013 May 15;95(10):e67. doi: 10.2106/JBJS.K.00805.
5
Expert Consensus for Early Onset Scoliosis Surgery.早发性脊柱侧弯手术专家共识
J Pediatr Orthop. 2020 Aug;40(7):e621-e628. doi: 10.1097/BPO.0000000000001473.
6
Serial casting for early onset scoliosis and its effects on health-related quality of life during and after discontinuation of treatment.早期发病脊柱侧凸的连续矫形治疗及其对治疗过程中和治疗结束后健康相关生活质量的影响。
Spine Deform. 2020 Dec;8(6):1361-1367. doi: 10.1007/s43390-020-00175-5. Epub 2020 Aug 5.
7
A report of two conservative approaches to early onset scoliosis: serial casting and bracing.两种保守治疗早发性脊柱侧凸方法的报告:连续矫形和支具治疗。
Spine Deform. 2021 Mar;9(2):595-602. doi: 10.1007/s43390-020-00213-2. Epub 2020 Sep 28.
8
Treatment of early-onset scoliosis: techniques, indications, and complications.早期脊柱侧凸的治疗:技术、适应证和并发症。
Chin Med J (Engl). 2020 Feb 5;133(3):351-357. doi: 10.1097/CM9.0000000000000614.
9
Serial Casting in Neuromuscular and Syndromic Early-onset Scoliosis (EOS) Can Delay Surgery Over 2 Years.神经肌肉型和综合征型早发性脊柱侧凸(EOS)的连续矫形可使手术延迟超过 2 年。
J Pediatr Orthop. 2020 Sep;40(8):e772-e779. doi: 10.1097/BPO.0000000000001568.
10
Spring distraction system for dynamic growth guidance of early onset scoliosis: two-year prospective follow-up of 24 patients.春蕾脊柱弹性生长系统治疗早发性脊柱侧凸的动态生长指导:24 例患者 2 年前瞻性随访。
Spine J. 2021 Apr;21(4):671-681. doi: 10.1016/j.spinee.2020.11.007. Epub 2020 Nov 20.

引用本文的文献

1
Evaluation and Treatment of Thoracic Insufficiency Syndrome and Early-Onset Scoliosis.胸廓发育不全综合征和早发性脊柱侧弯的评估与治疗
J Clin Med. 2025 Jan 24;14(3):753. doi: 10.3390/jcm14030753.
2
What's new in the pediatric spine?小儿脊柱领域有哪些新进展?
J Child Orthop. 2024 Dec 19;19(1):3-13. doi: 10.1177/18632521241309531. eCollection 2025 Feb.
3
Caregiver Values and Preferences Related to Surgical Decision-Making for Children with Medical Complexity.与患有复杂疾病儿童手术决策相关的照顾者价值观和偏好
J Pediatr. 2025 Jan;276:114366. doi: 10.1016/j.jpeds.2024.114366. Epub 2024 Oct 19.
4
Current Concepts in the Treatment of Early Onset Scoliosis.早发性脊柱侧弯治疗的当前概念
J Clin Med. 2024 Jul 31;13(15):4472. doi: 10.3390/jcm13154472.
5
Diagnostic and therapeutic strategies in early onset scoliosis: A current concept review.早发性脊柱侧弯的诊断与治疗策略:当前概念综述
J Child Orthop. 2024 Feb 4;18(2):113-123. doi: 10.1177/18632521241228141. eCollection 2024 Apr.
6
Evaluating consensus and uncertainty among treatment options for early-onset scoliosis: new generation and international perspectives.评估早发性脊柱侧凸治疗方案的共识和不确定性:新一代和国际视角。
Spine Deform. 2023 Sep;11(5):1271-1282. doi: 10.1007/s43390-023-00713-x. Epub 2023 Jun 6.