Hicks J M, Iosefsohn M
Clin Chem. 1987 Jun;33(6):817-9.
We evaluated the Abbott Vision system, to assess its suitability for use in the physician's office setting. We compared results from Vision for all the available analytes (alkaline phosphatase, urea nitrogen, cholesterol, creatinine, glucose, uric acid, and triglycerides) with results from the Kodak Ektachem 400 and 700. For all analytes, standard curve linearity, assessed with various dilutions of an analyte-supplemented serum pool, was within the ranges claimed by the manufacturer. Within-run precision (CV) for assays of these analytes ranged from 0.9% to 4.7%, run-to-run precision from 1.1% to 7.3%. Comparisons with other methods were generally very good except for a bias in results for blood urea nitrogen and alkaline phosphatase. Hemolysis (hemoglobin at 2.0 and 3.0 g/L) interferes with results for cholesterol, glucose, triglycerides, and uric acid in serum and whole blood. Bilirubin at 82 mg/L interferes with results for creatinine and triglycerides; at 120 mg/L it interferes with cholesterol, glucose, and uric acid results; and at 170 mg/L it interferes with alkaline phosphatase results. Triglycerides up to 5000 mg/L do not interfere with any of the tests. Calibration of the analyzer was stable for one month. We also compared the performance of a skilled operator with that of an unskilled operator and a physician.
我们对雅培视觉系统进行了评估，以评定其在医生办公室环境中的适用性。我们将视觉系统对所有可用分析物（碱性磷酸酶、尿素氮、胆固醇、肌酐、葡萄糖、尿酸和甘油三酯）的检测结果与柯达Ektachem 400和700的检测结果进行了比较。对于所有分析物，通过对添加分析物的血清池进行各种稀释来评估的标准曲线线性，均在制造商声称的范围内。这些分析物检测的批内精密度（CV）范围为0.9%至4.7%，批间精密度为1.1%至7.3%。除了血尿素氮和碱性磷酸酶的结果存在偏差外，与其他方法的比较总体上非常好。溶血（血红蛋白浓度为2.0和3.0 g/L）会干扰血清和全血中胆固醇、葡萄糖、甘油三酯和尿酸的检测结果。胆红素浓度为82 mg/L时会干扰肌酐和甘油三酯的检测结果；浓度为120 mg/L时会干扰胆固醇、葡萄糖和尿酸的检测结果；浓度为170 mg/L时会干扰碱性磷酸酶的检测结果。高达5000 mg/L的甘油三酯不会干扰任何一项检测。分析仪的校准在一个月内保持稳定。我们还比较了熟练操作人员与非熟练操作人员以及医生的操作表现。
